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R-(-)-Gossypol Acetic Acid

Known as: (-)-Gossypol Acetic Acid, (2,2'-Binaphthalene)-8,8'-dicarboxaldehyde, 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-(R)-5,5'-bis(1-methylethyl)-, (2R)-, compd. with acetic acid (1:1), GOSSYPOL ACETIC ACID, (R)- 
The orally bioavailable solvate of the R-(-) enantiomer of gossypol and acetic acid with potential antineoplastic activity. As a BH3 mimetic, R… 
National Institutes of Health

Papers overview

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2015
2015
There is an error in Fig 1. In Fig 1C, the y-axis should read: “Percentage of ethidium homodimer-1 positive dead cells.” Please… 
2010
2010
e13502 Background: AT-101 [R-(-)-gossypol acetic acid] (AT) is an orally-administered BH3 mimetic that lowers the threshold for… 
2010
2010
e17523 Background: AT-101 is an oral inhibitor of the anti-apoptotic Bcl proteins (Bcl-2, Bcl-XL, Bcl-W, and Mcl-1) and potent… 
2000
2000
Abstract(1′R, 2R)-, (1′R, 2S)-, (1′S, 2R)- and (1′S, 2S)-α-hydroxymetoprolol; (2R)- and (2S)-O-desmethylmetoprolol; and (2R)- and…