Quantitative Structure-Activity Relationship

Known as: Relationships, Quantitative Structure-Activity, Relationship, Quantitative Structure-Activity, Structure Activity Relationship, Quantitative 
A quantitative prediction of the biological, ecotoxicological or pharmaceutical activity of a molecule. It is based upon structure and activity… (More)
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Peptides derived from dietary proteins, have been reported to display significant antioxidant activity, which may exert notably… (More)
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Highly Cited
2015
Highly Cited
2015
Neural networks were widely used for quantitative structure-activity relationships (QSAR) in the 1990s. Because of various… (More)
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Highly Cited
2004
Highly Cited
2004
A large number of methods are available for modeling quantitative structure-activity relationships (QSAR). We examine the… (More)
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Highly Cited
2001
Highly Cited
2001
The human intestinal absorption of 241 drugs was evaluated. Three main methods were used to determine the human intestinal… (More)
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Highly Cited
1999
Highly Cited
1999
In this report, the quantitative structure-activity relationship (QSAR) analyses of substituted phenols, vitamin E derivatives… (More)
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Highly Cited
1996
Highly Cited
1996
A new hybrid method (GNN) combining a genetic algorithm and an artificial neural network has been developed for quantitative… (More)
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Highly Cited
1988
Highly Cited
1988
In an earlier article' the need was demonstrated for atomic physicochemical properties for three dimensional structure directed… (More)
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Highly Cited
1987
Highly Cited
1987
The variation in amino acid sequence within sets of peptides is described by three principal properties, z1, z2, and z3, per… (More)
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Highly Cited
1987
Highly Cited
1987
In an earlier paper (Ghose A. K.; Crippen, G. M. J. Comput. Chem. 1986, 7, 565) the need of atomic physicochemical properties for… (More)
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Highly Cited
1979
Highly Cited
1979
Multiple regression analysis is a basic statistical tool used for QSAR studies in drug design. However, there is a risk or… (More)
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