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Pyruvate Kinase

Known as: phosphoenol transphosphorylase, Pyruvate Kinase [Chemical/Ingredient], kinase pyruvate 
ATP:pyruvate 2-O-phosphotransferase. A phosphotransferase that catalyzes reversibly the phosphorylation of pyruvate to phosphoenolpyruvate in the… 
National Institutes of Health

Related topics

Related topics

21 relations
Anemia, HemolyticIn BloodPKLR genePKM gene

Narrower (6)

Deficiency of pyruvate kinaseM-Type Pyruvate KinaseM1-Type Pyruvate KinaseM2-Type Pyruvate Kinase

Broader (1)

Phosphotransferases, ATP

Papers overview

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Highly Cited
2010
Highly Cited
2010
Efficacy of RNAi targeting of pyruvate kinase M2 combined with cisplatin in a lung cancer model
PurposePyruvate kinase isoenzyme M2 (PKM2) is a key enzyme in aerobic glycolysis; inhibition of PKM2 leads to the tumor growth… 
Highly Cited
1983
Highly Cited
1983
Control of mitochondrial respiration. The contribution of the adenine nucleotide translocator depends on the ATP- and ADP-consuming enzymes.
Highly Cited
1982
Highly Cited
1982
Regulation of expression of liver‐specific enzymes
1. The expression of twelve liver‐specific enzymes was analysed in twenty‐one independent rat hepatoma x human somatic cell… 
Highly Cited
1980
Highly Cited
1980
Further enzymic characters of Trypanosoma cruzi and their evaluation for strain identification.
Highly Cited
1979
Highly Cited
1979
Inactivation of phosphofructokinase by glucagon in rat hepatocytes.
Highly Cited
1976
Highly Cited
1976
Liver cell heterogeneity. The distribution of pyruvate kinase and phosphoenolpyruvate carboxykinase (GTP) in the liver lobule of fed and starved rats.
Pyruvate kinase and phosphoenolpyruvate carboxykinase activities were determined in microdissected freeze-dried liver cells from… 
Highly Cited
1975
Highly Cited
1975
Metal and metal-ATP interactions with brain and cardiac adenylate cyclases.
Highly Cited
1975
Highly Cited
1975
Energy metabolism of spermatozoa. V. The Embden-Myerhof pathway of glycolysis: activities of pathway enzymes in hypotonically treated rabbit epididymal spermatozoa.
Review
1972
Review
1972
Isozyme studies on adult, regenerating, precancerous and developing liver in relation to findings in hepatomas.
Highly Cited
1969
Highly Cited
1969
Pyruvate kinase variants of the Alaskan king-crab. Evidence for a temperature-dependent interconversion between two forms having distinct and adaptive kinetic properties.
1. Pyruvate kinase of Alaskan king-crab leg muscle exists in two kinetically distinct forms, each of which displays a different… 
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