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Pyruvate Kinase

Known as: phosphoenol transphosphorylase, Pyruvate Kinase [Chemical/Ingredient], kinase pyruvate 
ATP:pyruvate 2-O-phosphotransferase. A phosphotransferase that catalyzes reversibly the phosphorylation of pyruvate to phosphoenolpyruvate in the… 
National Institutes of Health

Related topics

Related topics

21 relations
Anemia, HemolyticIn BloodPKLR genePKM gene

Narrower (6)

Deficiency of pyruvate kinaseM-Type Pyruvate KinaseM1-Type Pyruvate KinaseM2-Type Pyruvate Kinase

Broader (1)

Phosphotransferases, ATP

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Regulation of rat liver L-type pyruvate kinase mRNA by insulin and by fructose.
The effects have been studied of streptozotocin-induced diabetes and subsequent insulin administration or feeding of a high… 
Highly Cited
1992
Highly Cited
1992
Identical point mutations of the R-type pyruvate kinase (PK) cDNA found in unrelated PK variants associated with hereditary hemolytic anemia.
We cloned and sequenced the cDNAs for R-type pyruvate kinase (R-PK) from three homozygous PK patients. A point mutation (1151ACG… 
1986
1986
Complete amino acid sequence of rat L-type pyruvate kinase deduced from the cDNA sequence.
cDNA clones, containing the entire coding region of rat L-type pyruvate kinase, were isolated and their nucleotide sequences were… 
1980
1980
Phosphorylation of rat hepatic fructose-1,6-bisphosphatase and pyruvate kinase.
Fructose-1,6-bisphosphatase from rat liver was phosphorylated with cyclic AMP-dependent protein kinase and [gamma-32P]ATP. Brief… 
1977
1977
Studies on the cyclic 3':5'-AMP-stimulated pig liver protein kinase reaction with pyruvate kinase as substrate.
The phosphorylation of pig liver pyruvate kinase by cyclic adenosine 3':5'-monophosphate-dependent protein kinase has been… 
Highly Cited
1976
Highly Cited
1976
Chromium(III)-adenosine triphosphate as a paramagnetic probe to determine intersubstrate distances on pyruvate kinase. Detection of an active enzyme-metal-ATP-metal complex.
The interaction of CrATP, a stable, substitution-inert, paramagnetic tridentate complex of ATP, with muscle pyruvate kinase has… 
Highly Cited
1971
Highly Cited
1971
Role of lysyl epsilon-amino groups in adenosine diphosphate binding and catalytic activity of pyruvate kinase.
Abstract Rabbit muscle pyruvate kinase is inactivated by trinitrobenzene sulfonate, a compound known to attack amino and… 
Highly Cited
1970
Highly Cited
1970
Regulation of gluconeogenesis in the guinea pig liver.
Because of differences in the pattern of enzyme activities involved in glycolysis and gluconeo-genesis between rat and guinea pig… 
Highly Cited
1969
Highly Cited
1969
Yeast pyruvate kinase. II. Kinetic properties.
Abstract The kinetic properties of purified yeast pyruvate kinase were investigated. The enzyme showed cooperative kinetics… 
Highly Cited
1958
Highly Cited
1958
The pathway of hexose synthesis from pyruvate in muscle.
Although most of the reactions involved in the interconversion of glycogen and pyruvic acid are reversible, there is reason to… 
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