Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Pyruvate Kinase

Known as: phosphoenol transphosphorylase, Pyruvate Kinase [Chemical/Ingredient], kinase pyruvate 
ATP:pyruvate 2-O-phosphotransferase. A phosphotransferase that catalyzes reversibly the phosphorylation of pyruvate to phosphoenolpyruvate in the… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
The major cell classes of the brain differ in their developmental processes, metabolism, signaling, and function. To better… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Pyruvate kinase isoform M2 (PKM2) is a glycolysis enzyme catalyzing conversion of phosphoenolpyruvate (PEP) to pyruvate by… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Cancer cells engage in a metabolic program to enhance biosynthesis and support cell proliferation. The regulatory properties of… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
The pyruvate kinase isoforms PKM1 and PKM2 are alternatively spliced products of the PKM2 gene. PKM2, but not PKM1, alters… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
The glycolytic metabolism of cancers differs from normal tissues, allowing tumor cells to survive under oxidative stress. Control… Expand
Is this relevant?
Highly Cited
2010
Highly Cited
2010
When oxygen is abundant, quiescent cells efficiently extract energy from glucose primarily by oxidative phosphorylation, whereas… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Many tumour cells have elevated rates of glucose uptake but reduced rates of oxidative phosphorylation. This persistence of high… Expand
  • figure 1
  • figure 3
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Growth factors stimulate cells to take up excess nutrients and to use them for anabolic processes. The biochemical mechanism by… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2005
Review
2005
Proliferating cells and tumor cells in particular express the pyruvate kinase isoenzyme type M2 (M2-PK). Within the tumor… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
BACKGROUND Yeast pyruvate kinase (PK) catalyzes the final step in glycolysis. The enzyme therefore represents an important… Expand
  • figure 1
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Is this relevant?