Prothionamide

Known as: 2-Propylpyridine-4-carbothioamide, Prothionamide [Chemical/Ingredient], 4-Pyridinecarbothioamide, 2-propyl- 
A thioamide derivative with antitubercular activity. Protionamide forms a covalent adduct with bacterial nicotinamide adenine dinucleotide (NAD), PTH… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1966-2018
051019662018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
2486 www.thelancet.com Vol 387 June 18, 2016 Tuberculosis is now the world’s commonest cause of death from infectious disease… (More)
Is this relevant?
Highly Cited
2013
Highly Cited
2013
The broadest pattern of tuberculosis (TB) drug resistance for which a consensus definition exists is extensively drug-resistant… (More)
Is this relevant?
2013
2013
With mycobacteriosis increasing, the study of non-tuberculous mycobacteria is imperative for clinical therapy and management. Non… (More)
Is this relevant?
2009
2009
SETTING National Masan Tuberculosis Hospital, Masan, South Korea. OBJECTIVE To evaluate the pharmacokinetics of prothionamide… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
The BACTEC MGIT 960 system, a fully automated, nonradiometric, noninvasive system for detection and drug susceptibility testing… (More)
  • table 1
  • table 2
  • table 3
  • table 5
  • table 4
Is this relevant?
2006
2006
In 1982-1984 we conducted a six-month clinical trial in 50 previously untreated lepromatous leprosy patients randomly assigned to… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
The objectives of this study were to (i) compare agreement of the MGIT 960 system for first-line drugs with a methodology (the… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
OBJECTIVE To compare levofloxacin and ofloxacin in the treatment of multidrug-resistant tuberculosis (MDR-TB). PATIENTS AND… (More)
  • table 1
  • table 2
  • figure 1
  • table 3
  • table 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
OBJECTIVE To analyze outcomes of patients with multidrug-resistant tuberculosis (MDR-TB) treated with ofloxacin/levofloxacin… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • table 5
Is this relevant?
1995
1995
Resistance of Mycobacterium tuberculosis (M.tb) strains is an increasing problem worldwide. Since no public health data are… (More)
Is this relevant?