Skip to search formSkip to main contentSkip to account menu

Proteus Syndrome

Known as: Elephant Man Disease, disease elephant mans, Proteus Syndrome [Disease/Finding] 
Hamartoneoplastic malformation syndrome of uncertain etiology characterized by partial GIGANTISM of the hands and/or feet, asymmetry of the limbs… 
National Institutes of Health

Related topics

Related topics

27 relations
AcanthosisBlepharoptosisCapillary malformation (disorder)Congenital anomaly of brain

Narrower (1)

Macrocephaly mesodermal hamartoma spectrum

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Mosaic Disorders of the PI3K/PTEN/AKT/TSC/mTORC1 Signaling Pathway.
Review
2014
Review
2014
Proteus syndrome review: molecular, clinical, and pathologic features
Proteus syndrome is caused by an activating AKT1 mutation (c.49G>A, p.Glu17Lys). Many variable features are possible in this… 
Highly Cited
2009
Highly Cited
2009
Surgery for acute type A dissection using total arch replacement combined with stented elephant trunk implantation: experience with 107 patients.
Highly Cited
2006
Highly Cited
2006
Proteus Syndrome
Proteus… 
Review
2004
Review
2004
Cutaneous manifestations of proteus syndrome: correlations with general clinical severity.
BACKGROUND Proteus syndrome is a rare congenital disorder with progressive asymetric overgrowth of multiple tissues. OBJECTIVES… 
Review
2003
Review
2003
PTEN: One Gene, Many Syndromes
PTEN, on 10q23.3, encodes a major lipid phosphatase which signals down the phosphoinositol‐3‐kinase/Akt pathway and effects G1… 
Highly Cited
2002
Highly Cited
2002
Germline mutation of the tumour suppressor PTEN in Proteus syndrome
Proteus syndrome (PS, OMIM 176920) is a hamartomatous disorder characterised by overgrowth of multiple tissues, connective tissue… 
Review
1995
Review
1995
Neoplasms in Proteus syndrome.
We report on 2 children with Proteus syndrome who developed neoplasms. Patient 1 had a probable mesothelioma, although papillary… 
Highly Cited
1992
Highly Cited
1992
Mental images can be ambiguous: Reconstruals and reference-frame reversals
Philosophers and psychologists have debated whether or not mental images of ambiguous-figures are reversible as pictures of such… 
Highly Cited
1986
Highly Cited
1986
The Proteus syndrome: the Elephant Man diagnosed.
Sir Frederick Treves first showed Joseph Merrick, the famous Elephant Man, to the Pathological Society of London in 1884. A… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)