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Protein Targeting

Known as: Protein Localization Processes, Cellular, Targeting, Protein, protein target 
The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an… 
National Institutes of Health

Related topics

Related topics

3 relations
'de novo' cotranslational protein foldingregulation of protein targeting

Broader (1)

protein transport

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Fluorescence anisotropy analysis for mapping aptamer-protein interaction at the single nucleotide level.
Structural characterization of aptamer-protein interactions is challenging and limited despite the tremendous applications of… 
Highly Cited
2010
Highly Cited
2010
Determinants for Stop-transfer and Post-import Pathways for Protein Targeting to the Chloroplast Inner Envelope Membrane*
The inner envelope membrane (IEM) of the chloroplast plays key roles in controlling metabolite transport between the organelle… 
Highly Cited
2006
Highly Cited
2006
Comparison of different strategies to select aptamers against a transmembrane protein target.
Binding of aptamers is dependent on their target conformation, which in turn is conditioned by the target's environment… 
Highly Cited
2005
Highly Cited
2005
Ku protein targeting by Ku70 small interfering RNA enhances human cancer cell response to topoisomerase II inhibitor and γ radiation
Ku protein is a heterodimer (Ku70 and Ku86) known to play an important role in V(D)J recombination, apoptosis, telomere fusion… 
Highly Cited
2004
Highly Cited
2004
Targeting a binding pocket within the trimer-of-hairpins: small-molecule inhibition of viral fusion.
Trimeric class I virus fusion proteins undergo a series of conformational rearrangements that leads to the association of C- and… 
2003
2003
Surface expression of heterogeneous nuclear RNA binding protein M4 on Kupffer cell relates to its function as a carcinoembryonic antigen receptor.
2000
2000
Selection of genetic agents from random peptide aptamer expression libraries.
Highly Cited
1997
Highly Cited
1997
The cytoplasmic and transmembrane domains of the vaccinia virus B5R protein target a chimeric human immunodeficiency virus type 1 glycoprotein to the outer envelope of nascent vaccinia virions
The outer envelope of the extracellular form of vaccinia virus (EEV) is derived from the Golgi membrane and contains at least six… 
Highly Cited
1989
Highly Cited
1989
Selective acetaminophen metabolite binding to hepatic and extrahepatic proteins: an in vivo and in vitro analysis.
Highly Cited
1985
Highly Cited
1985
Arginine in the leader peptide is required for both import and proteolytic cleavage of a mitochondrial precursor.
Most mitochondrial proteins are encoded in the nucleus and translated in the cytoplasm as larger precursors containing NH2… 
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