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Protac snake venom protein C activator

Known as: Protac 
 
National Institutes of Health

Papers overview

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2020
2020
Targeting protein degradation with Proteolysis-Targeting Chimeras (PROTACs) is an area of great current interest in drug… Expand
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2019
2019
Although the number of proteins effectively targeted for posttranslational degradation by PROTAC has grown steadily, the number… Expand
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2019
2019
The impact of covalent binding on PROTAC-mediated degradation of BTK was investigated through the preparation of both covalent… Expand
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2019
2019
Small-molecule heterobifunctional degraders can effectively control protein levels and are useful research tools. We assembled… Expand
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2019
2019
While the use of ATP-competitive tyrosine kinase inhibitors of oncoprotein BCR-ABL1 has enabled durable responses in patients… Expand
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2019
2019
Proteolysis targeting chimeras (PROTACs) are an emerging strategy for promoting targeted protein degradation by inducing the… Expand
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Highly Cited
2017
Highly Cited
2017
Inducing macromolecular interactions with small molecules to activate cellular signaling is a challenging goal. PROTACs… Expand
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2014
2014
The X-protein of the hepatitis B virus (HBV) is essential for virus infection and contributes to the development of HBV-induced… Expand
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2004
2004
A novel strategy that targets protein for degradation has recently been developed by exploiting a protein-targeting chimeric… Expand
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Highly Cited
2003
Highly Cited
2003
The proteome contains hundreds of proteins that in theory could be excellent therapeutic targets for the treatment of human… Expand
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