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Prostate Health Index

Known as: phi, phi-index 
An assay system that indirectly measures the amount of three forms of prostate-specific antigen (PSA) in a patient serum sample and then uses those… 
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
Combining Prostate Health Index density, magnetic resonance imaging and prior negative biopsy status to improve the detection of clinically significant prostate cancer
To determine the performance of Prostate Health Index (PHI) density (PHID) combined with MRI and prior negative biopsy (PNB… 
Highly Cited
2017
Highly Cited
2017
Prostate Health Index density improves detection of clinically significant prostate cancer
To explore the utility of Prostate Health Index (PHI) density for the detection of clinically significant prostate cancer (PCa… 
Highly Cited
2016
Highly Cited
2016
The Prostate Health Index adds predictive value to multi-parametric MRI in detecting significant prostate cancers in a repeat biopsy population
Both multi-parametric MRI (mpMRI) and the Prostate Health Index (PHI) have shown promise in predicting a positive biopsy in men… 
Highly Cited
2016
Highly Cited
2016
USE OF THE PROSTATE HEALTH INDEX FOR DETECTION OF PROSTATE CANCER: RESULTS FROM A LARGE ACADEMIC PRACTICE
Background:The Prostate Health Index (phi) outperforms PSA and other PSA derivatives for the diagnosis of prostate cancer (PCa… 
Highly Cited
2016
Highly Cited
2016
The percentage of prostate‐specific antigen (PSA) isoform [–2]proPSA and the Prostate Health Index improve the diagnostic accuracy for clinically relevant prostate cancer at initial and repeat biopsy…
To prospectively test the diagnostic accuracy of the percentage of prostate specific antigen (PSA) isoform [–2]proPSA (%p2PSA… 
Highly Cited
2015
Highly Cited
2015
The prostate health index selectively identifies clinically significant prostate cancer.
Highly Cited
2014
Highly Cited
2014
Diagnostic ability of %p2PSA and prostate health index for aggressive prostate cancer: a meta-analysis
The role of [-2]proPSA (p2PSA) based diagnostic tests for the detection of aggressive prostate cancer (PCa) has not been fully… 
Highly Cited
2013
Highly Cited
2013
Serum isoform [-2]proPSA derivatives significantly improve prediction of prostate cancer at initial biopsy in a total PSA range of 2-10 ng/ml: a multicentric European study.
Highly Cited
2013
Highly Cited
2013
Prostate Health Index (Phi) and Prostate Cancer Antigen 3 (PCA3) Significantly Improve Prostate Cancer Detection at Initial Biopsy in a Total PSA Range of 2–10 ng/ml
Many efforts to reduce prostate specific antigen (PSA) overdiagnosis and overtreatment have been made. To this aim, Prostate… 
Review
2012
Review
2012
Evaluation of [−2] proPSA and Prostate Health Index (phi) for the detection of prostate cancer: a systematic review and meta-analysis
Abstract The usefulness of %[−2] proPSA and Prostate Health Index (phi) in the detection of prostate cancer are currently unknown… 
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