Pronucleus

The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
The epigenomes of early mammalian embryos are extensively reprogrammed to acquire a totipotent developmental potential. A major… (More)
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Highly Cited
2011
Highly Cited
2011
Genome-wide erasure of DNA cytosine-5 methylation has been reported to occur along the paternal pronucleus in fertilized oocytes… (More)
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Highly Cited
2010
Highly Cited
2010
Genome-wide active DNA demethylation in primordial germ cells (PGCs), which reprograms the epigenome for totipotency, is linked… (More)
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Review
2007
Review
2007
Current treatments of subfertile couples are usually empiric, as the true cause of subfertility often remains unknown. Therefore… (More)
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Highly Cited
2004
Highly Cited
2004
Tri-methylated lysine 20 on histone H4 (Me(3)K20H4) is a marker of constitutive heterochromatin in murine interphase and… (More)
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2004
2004
Sperm-specific phospholipase C zeta (PLC zeta) is known to induce intracellular Ca(2+) oscillations and egg activation when… (More)
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Highly Cited
2001
Highly Cited
2001
The introduction of two transgenes into one animal is increasingly common as transgenic experiments become more sophisticated. In… (More)
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Highly Cited
1999
Highly Cited
1999
We have investigated the role of cytoplasmic dynein in microtubule organizing center (MTOC) positioning using RNA-mediated… (More)
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Highly Cited
1998
Highly Cited
1998
We present the first evidence that genetically damaged human spermatozoa are able to form normal pronuclei in oocytes after… (More)
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Highly Cited
1995
Highly Cited
1995
To examine whether mtDNA is uni- or biparentally transmitted in mice, we developed an assay that can detect sperm mtDNA in a… (More)
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