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Prolyl-Hydroxylase Inhibitors

Known as: Inhibitors, Prolyl-Hydroxylase, Hydroxylase Inhibitors, Proline, Proline Hydroxylase Inhibitors 
Compounds that inhibit the action of HYDROXYLASES that act on PROLINE to form HYDROXYPROLINE.
National Institutes of Health

Papers overview

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2017
2017
目的:以目标靶蛋白为研究对象设计一系列可口服的抗贫血类化学药物分子结构。方法:本文针对肾性和肿瘤相关性贫血设计口服小分子治疗药物。贫血,特别是糖尿病性贫血治疗领域是一个非常有前景的市场。HIF-PHD… 
Review
2017
Review
2017
Anemia is a common complication of chronic kidney disease (CKD) associated with disease progression and increased mortality. This… 
2016
2016
Small-molecule stabilizers of hypoxia inducible factor (HIF) are being developed for the treatment of renal anaemia. These… 
2014
2014
Despite improvements in survival rates for childhood cancer over recent decades, a number of malignancies remain refractory to… 
2012
2012
In this study, we stimulated the formation of capillary-like structure from human umbilical vein endothelial cells (HUVEC) by… 
2012
2012
The present invention is, polymorphs, their preparation including the preparation of intermediates and pharmaceutical… 
1991
1991
Peptidyl proline hydroxylase inhibitors block the growth of cultured soybean (Glycine max) cells and bring about the…