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Procysteine

National Institutes of Health

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2-oxothiazolidine-4-carboxylic acid

Papers overview

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2012
2012
The role of mitochondrial oxidation in endotoxin-induced liver-dependent swine pulmonary edema.
2011
2011
Thiols stabilize cobblestone morphology of cultured mesothelial cells
Cellular thiols including GSH (glutathione) and l‐Cys (l‐cysteine) are essential for cell signalling, growth and differentiation… 
2007
2007
Alveolar type II cells from ethanol-fed rats produce a fibronectin-enriched extracellular matrix that promotes monocyte activation.
Highly Cited
2002
Highly Cited
2002
Glutathione replacement preserves the functional surfactant phospholipid pool size and decreases sepsis-mediated lung dysfunction in ethanol-fed rats.
BACKGROUND Alcohol abuse increases the incidence of acute respiratory distress syndrome (ARDS). Previous evidence from our… 
1997
1997
Protective effects of L-2-oxothiazolidine-4-carboxylate treatment on cyclophosphamide-induced cystitis in rats.
1996
1996
Supplementation with L-2-oxothiazolidine-4-carboxylic acid, a cysteine precursor, does not protect against lipid peroxidation in puromycin aminonucleoside-induced nephropathy.
Lipid peroxidation in the kidney has been shown to precede proteinuria in puromycin aminonucleoside (PAN)-induced nephropathy… 
1995
1995
L-2-oxothiazolidine-4-carboxylic acid (procysteine) inhibits expression of the human immunodeficiency virus and expression of the interleukin-2 receptor alpha chain.
These studies were undertaken to examine the in vitro effects of the cysteine pro-drug L-2-oxothiazolidine-4-carboxylic acid… 
1994
1994
A phase I/II trial of intravenous L-2-oxothiazolidine-4-carboxylic acid (procysteine) in asymptomatic HIV-infected subjects.
Twenty-four asymptomatic, HIV-1-seropositive subjects with CD4 cell counts of > or = 400/microliters participated in a Phase I/II… 
1994
1994
Development of a novel glutathione repleting agent, L-2-oxothiazolidine-4-carboxylic acid (Procysteine®)
A number of disease states are associated with episodes of acute or chronic oxidative stress, including Acute Respiratory… 
1993
1993
Enhancement of viability of human peritoneal mesothelial cells with glutathione precursor: L-2-oxothiazolidine-4-carboxylate.
This study tested the effect of L-2-oxothiazolidine-4-carboxylate (procysteine), a precursor of the intracellular cysteine, on… 
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