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Primary Endpoint

The main result that is measured at the end of a study to see if a given treatment worked (e.g., the number of deaths or the difference in survival… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
BACKGROUND Despite the acknowledged sex-related dimorphism in immune system response, little is known about the effect of… Expand
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Review
2016
Review
2016
Eravacycline is an investigational, synthetic fluorocycline antibacterial agent that is structurally similar to tigecycline with… Expand
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Nivolumab, a fully human IgG4 PD-1 immune checkpoint inhibitor antibody, can result in durable responses in patients… Expand
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Highly Cited
2013
Highly Cited
2013
BACKGROUND No treatment options are available for patients with metastatic colorectal cancer that progresses after all approved… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Erlotinib has been shown to improve progression-free survival compared with chemotherapy when given as first-line… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Drug treatments for patients with high-risk myelodysplastic syndromes provide no survival advantage. In this trial, we… Expand
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Review
2008
Review
2008
The design of clinical trials in hepatocellular carcinoma (HCC) is complex because many patients have concurrent liver disease… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Epidemiological and clinical evidence suggests that an increased intake of long-chain n-3 fatty acids protects against… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Although statins reduce coronary and cerebrovascular morbidity and mortality in middle-aged individuals, their… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND There is conflicting evidence on the benefits of foods rich in vitamin E (alpha-tocopherol), n-3 polyunsaturated fatty… Expand
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