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Pretibial myxedema

Known as: myxedema pretibial, pretibial myxoedema 
A diffuse, non-pitting edema and thickening of the skin usually on the anterior aspect of the lower legs spreading to the dorsum of the feet. [HPO… 
National Institutes of Health

Related topics

Related topics

2 relations
Hypothyroidism

Broader (1)

Myxedema

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Pretibial myxedema as the initial manifestation of Graves’ disease
Pretibial myxedema (PM) is a localized thickening of the pretibial skin due to accumulation of acid mucopolysacharides… 
Highly Cited
2002
Highly Cited
2002
Evidence for thyrotropin receptor immunoreactivity in pretibial connective tissue from patients with thyroid-associated dermopathy.
Pretibial myxedema (PTM), mainly characterized by the accumulation of glycosaminoglycans in the dermis and subcutaneous tissue… 
2000
2000
Refractory pretibial myxoedema with response to intralesional insulin‐like growth factor 1 antagonist (octreotide): downregulation of hyaluronic acid production by the lesional fibroblasts
We report a case of refractory pretibial myxoedema (PTM) with Graves’ disease in which there was a good clinical response to… 
1994
1994
Echographic diagnosis of pretibial myxedema in patients with autoimmune thyroid disease.
In the present study we have evaluated the use of pretibial ultrasound for the diagnosis of pretibial myxedema (PTM). We studied… 
Highly Cited
1993
Highly Cited
1993
Pentoxifylline inhibits the proliferation and glycosaminoglycan synthesis of cultured fibroblasts derived from patients with Graves' ophthalmopathy and pretibial myxoedema.
Excessive amounts of glycosaminoglycans accumulate in the extraocular muscles of patients with Graves' ophthalmopathy and in the… 
Review
1993
Review
1993
Pretibial mucin. Histologic patterns and clinical correlation.
BACKGROUND AND OBJECTIVE We identified several patients with a histologic diagnosis of pretibial myxedema in whom thyroid disease… 
Highly Cited
1993
Highly Cited
1993
Pretibial myxoedema: a manifestation of lymphoedema?
1980
1980
Ultrastructural and Immunological Findings in Graves' Disease with Pretibial Myxedema *
This is a report on a 67‐year‐old female patient with Graves' disease and extensive pretibial myxedema. Linear IgM deposits were… 
Review
1978
Review
1978
Stimulation of fibroblast biosynthetic activity by serum of patients with pretibial myxedema.
Skin fibroblasts from the shoulder and lower extremities of normal individuals, as well as from patients with pretibial myxedema… 
1959
1959
Mucopolysaccharide content of skin in patients with pretibial myxedema.
It is well-known that the skin of patients with primary and secondary myxedema contains a mucinous infiltrate. This extracellular… 
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