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Prefrontal Cortex

Known as: Prefrontal association cortex, prefrontal lobe, Cortex, Prefrontal 
The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the MEDIODORSAL… 
National Institutes of Health

Related topics

Related topics

34 relations
Amygdaloid structureBlood supply aspectsCerebral cortexCorpora quadrigemina, superior colliculus

Narrower (10)

Frontal SulcusInferior frontal gyrusLateral Orbitofrontal CortexOrbitofrontal cortex

Broader (1)

frontal lobe

Papers overview

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Highly Cited
2007
Highly Cited
2007
Cannabinoids Elicit Antidepressant-Like Behavior and Activate Serotonergic Neurons through the Medial Prefrontal Cortex
Preclinical and clinical studies show that cannabis modulates mood and possesses antidepressant-like properties, mediated by the… 
Highly Cited
2005
Highly Cited
2005
Lesions of Medial Prefrontal Cortex Disrupt the Acquisition But Not the Expression of Goal-Directed Learning
Several studies have established that pretraining lesions of the medial prefrontal cortex (mPFC) render instrumental actions… 
Highly Cited
2005
Highly Cited
2005
Involvement of 5-HT1A Receptors in Prefrontal Cortex in the Modulation of Dopaminergic Activity: Role in Atypical Antipsychotic Action
Atypical antipsychotics increase dopamine (DA) release in the medial prefrontal cortex (mPFC), an effect possibly involved in the… 
Highly Cited
2002
Highly Cited
2002
Reduced neuronal size and glial cell density in area 9 of the dorsolateral prefrontal cortex in subjects with major depressive disorder.
Reductions in glial cell density and neuronal size have been described recently in major depressive disorder (MDD). Considering… 
Highly Cited
2000
Highly Cited
2000
GABA‐containing neurons in the rat ventral tegmental area project to the prefrontal cortex
Dopamine‐containing projections from the ventral tegmental area (VTA) to the prefrontal cortex (PFC) have been extensively… 
Highly Cited
1999
Highly Cited
1999
Effects of antipsychotic drugs on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens.
The present study was designed to compare the effects of typical and atypical antipsychotic drugs on extracellular dopamine (DA… 
Highly Cited
1996
Highly Cited
1996
The Prefrontal Cortex Regulates the Basal Release of Dopamine in the Limbic Striatum: An Effect Mediated by Ventral Tegmental Area
Abstract: The present study examined whether the prefrontal cortex (PFC) exerts a tonic control over the basal release of… 
Highly Cited
1995
Highly Cited
1995
Information coding in the rodent prefrontal cortex. I. Single-neuron activity in orbitofrontal cortex compared with that in pyriform cortex.
1. Extracellular spike activity was recorded from 1,942 single neurons in orbitofrontal cortex (OF) and 591 single neurons in… 
Highly Cited
1995
Highly Cited
1995
Highly restricted origin of prefrontal cortical inputs to striosomes in the macaque monkey
The prefrontal cortex is made up of neocortical areas thought to mediate aspects of the temporal and spatial organization of… 
Review
1979
Review
1979
Gonadal hormones and sex differences in nonreproductive behaviors in rodents: Organizational and activational influences
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