Pre-mRNA 3'-End-Processing Factor FIP1

Known as: Rhe, Factor Interacting with PAP, hFip1 
Pre-mRNA 3'-end-processing factor FIP1 (594 aa, ~67 kDa) is encoded by the human FIP1L1 gene. This protein is involved in the polyadenylation of mRNA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
051019992017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Genome instability via RNA:DNA hybrid-mediated R loops has been observed in mutants involved in various aspects of transcription… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND AND OBJECTIVES The hypereosinophilic syndrome (HES) may be associated with the fusion of the platelet derived growth… (More)
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2007
2007
An interstitial deletion on chromosome 4q12 resulting in the formation of the FIP1L1-PDGFRA fusion protein is involved in the… (More)
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2006
2006
Genetic abnormalities that result in expression of chimeric tyrosine kinase proteins such as BCR-ABL1 and ETV6-PDGFRbeta are… (More)
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Highly Cited
2005
Highly Cited
2005
At least half of all human pre-mRNAs are subject to alternative 3' processing that may modulate both the coding capacity of the… (More)
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2005
2005
Idiopathic hypereosinophilic syndrome (HES) characterized by unexplained and persistent hypereosinophilia is heterogeneous and… (More)
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Highly Cited
2004
Highly Cited
2004
In mammals, polyadenylation of mRNA precursors (pre-mRNAs) by poly(A) polymerase (PAP) depends on cleavage and polyadenylation… (More)
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2004
2004
We recently identified the chimeric kinase FIP1L1-platelet-derived growth factor receptor alpha (PDGFRalpha) as a cause of the… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Idiopathic hypereosinophilic syndrome involves a prolonged state of eosinophilia associated with organ dysfunction. It… (More)
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Highly Cited
2003
Highly Cited
2003
Imatinib mesylate is effective in the treatment of hematologic malignancies that are characterized by either abl- or PDGFR beta… (More)
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