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Prajmaline

Known as: Ajmalanium, 17,21-dihydroxy-4-propyl-, (17R,21alpha)-, N-Propylajmaline, Prajmaline [Chemical/Ingredient] 
A derivative of the rauwolfia alkaloid AJMALINE. It is an anti-arrhythmia agent, but may cause liver damage.
National Institutes of Health

Related topics

Related topics

10 relations

Broader (1)

Anti-Arrhythmia Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (2)

Neo-GilurytmalPrajmalium Bitartrate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1990
1990
Comparative Analysis of the Action of Class I Antiarrhythmic Drugs (Lidocaine, Quinidine, and Prajmaline) in Rabbit Atrial and Ventricular Myocardium
Effects of three class I antiarrhythmic drugs (quinidine, lidocaine, and prajmaline) on transmembrane resting (RMP) and action… 
1985
1985
Pharmacokinetics of N-propylajmaline in relation to polymorphic sparteine oxidation
SummaryIn order to determine whether the metabolism of the antiarrhythmic drug N-propylajmaline is under the same genetic control… 
1983
1983
Comparison of tocainide and prajmalium bitartrate for the treatment of ventricular arrhythmias.
The antiarrhythmic efficacy of tocainide, a new antiarrhythmic substance, has been compared with that of prajmalium bitartrate, a… 
1981
1981
Evaluation of prajmalium-induced cholestasis by immunologic tests.
Cholestatic jaundice developed in four patients after the administration of prajmalium bitartrate. The clinical, histologic… 
1981
1981
Experience with immunological tests in drug-induced hepatitis.
Nine patients are reported who developed hepatic injury following the administration of therapeutic agents. The drugs… 
1978
1978
Pharmacokinetic studies of the antiarrhythmic drugs ajmaline and N-propylajmaline bitartrate in dogs.
A rapid, sensitive fluorometric method for the determination of ajmaline and N-propylajmaline (NPA) was used to follow serum… 
1978
1978
[Oral prajmalium bitartrate and intravenous lidocaine in the control of arrhythmias in acute myocardial infarction (author's transl)].
1976
1976
[Prajmalium bitartrat-induced liver damage (author's transl)].
Liver damage was found in five patients (three men, two women) who were receiving prajmalium bitartrate. The cause was proven by… 
1976
1976
[Effect of prajmalium bitartrate and procaine amide on ventricular extrasystoles (author's transl)].
Prajmalium bitartrate (Neo-Gilurytmal) was given to 19 patients, who had either runs of ventricular extrasystoles or frequent… 
1976
1976
[Intrahepatic cholestasis caused by prajmalium bitartrate].
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