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Prajmaline

Known as: Ajmalanium, 17,21-dihydroxy-4-propyl-, (17R,21alpha)-, N-Propylajmaline, Prajmaline [Chemical/Ingredient] 
A derivative of the rauwolfia alkaloid AJMALINE. It is an anti-arrhythmia agent, but may cause liver damage.
National Institutes of Health

Papers overview

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2005
2005
SummaryIn order to determine whether the metabolism of the antiarrhythmic drug N-propylajmaline is under the same genetic control… Expand
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2004
2004
Summary1.The negative inotropic effect and the effect on action potential configuration were investigated for TTX and 7 class 1… Expand
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Highly Cited
1999
Highly Cited
1999
Organic anion transporting polypeptide (oatp1) has been cloned from rat liver as one of the transporters responsible for the… Expand
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Highly Cited
1996
Highly Cited
1996
An organic anion-transporting polypeptide that mediates sodium-independent uptake of negatively charged sulfobromophthalein and… Expand
Highly Cited
1990
Highly Cited
1990
120 cases of class IC antiarrhythmic overdose, including propafenone, flecainide, ajmaline and prajmaline overdose, were… Expand
Highly Cited
1990
Highly Cited
1990
The frequency-dependent block of cardiac sodium channels by class 1 antiarrhythmic drugs can be described by a periodical ligand… Expand
1989
1989
In patch-clamped membranes from neonatal rat cardiocytes, elementary Na+ currents were recorded at 19°C for study of the… Expand
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Review
1989
Review
1989
Negative inotropic effects of antiarrhythmic drugs are ultimately mediated by alterations of intracellular Ca++. With class I… Expand
1987
1987
The case history is documented of a young competitive athlete known to have the electrocardiographic pattern of the Wolff… Expand
1978
1978
Abstract The effect of orally administered prajmalium bitartrate on premature ventricular complexes and on runs of such complexes… Expand