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Poorly Differentiated Neuroblastoma

A neuroblastoma in which the differentiating neuroblasts constitute less than five-percent of the tumor cells.
National Institutes of Health

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Related topics

14 relations
Embryonic CellEmbryonic tissueHemorrhageLoss of Chromosome 1p
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Reversible LSD1 inhibition with HCI-2509 induces the p53 gene expression signature and disrupts the MYCN signature in high-risk neuroblastoma cells
Lysine-Specific Demethylase 1 (LSD1) over-expression correlates with poorly differentiated neuroblastoma and predicts poor… Expand
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2018
2018
High Oct4 expression: implications in the pathogenesis of neuroblastic tumours
BackgroundNeuroblastic tumours (NBTs) are paediatric solid tumours derived from embryonic neural crest cells which harbour their… Expand
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Highly Cited
2012
Highly Cited
2012
PI3K/AKT and ERK regulate retinoic acid-induced neuroblastoma cellular differentiation.
Neuroblastoma, the most common extra-cranial solid tumor in infants and children, is characterized by a high rate of spontaneous… Expand
Highly Cited
2009
Highly Cited
2009
Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy.
Aberrant epigenetic changes in DNA methylation and histone acetylation are hallmarks of most cancers, whereas histone methylation… Expand
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Review
2008
Review
2008
Pathology of peripheral neuroblastic tumors: Significance of prominent nucleoli in undifferentiated/poorly differentiated neuroblastoma
The presence of large cells having simultaneously increased cytoplasmic and nuclear volume accompanied by prominent nucleoli; i.e… Expand
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2000
2000
Angiogenesis and neuroblastomas: interleukin-8 and interleukin-8 receptor expression in human neuroblastoma.
PURPOSE Studies have demonstrated that the pro-angiogenic cytokine interleukin-8 (IL-8) and the IL-8 receptors likely have a role… Expand
1995
1995
Poorly differentiated pediatric head and neck neuroblastoma: a diagnostic dilemma.
Primary pediatric head and neck neuroblastoma is rare, with metastatic disease being the more common mode of involvement in this… Expand
Highly Cited
1994
Highly Cited
1994
The Ewing family of tumors--a subgroup of small-round-cell tumors defined by specific chimeric transcripts.
BACKGROUND Precise diagnosis of small-round-cell tumors is often a challenge to the pathologist and the clinical oncologist. In… Expand
Review
1994
Review
1994
MANAGEMENT OF CHEMOTHERAPY IN A PREGNANCY COMPLICATED BY A LARGE NEUROBLASTOMA
Background: The English literature contains infrequent reports of neuroendocrine carcinoma during pregnancy. The chemotherapy for… Expand
1981
1981
Composite ganglioneuroblastoma. An assessment of the significance of histological maturation in neuroblastoma diagnosed beyond infancy.
At Cincinnati Childrens Hospital Medical Center, 19 cases of composite ganglioneuroblastoma (CGNB) comprise one third of the… Expand
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