Polymorphous corneal dystrophy

Known as: CORNEAL DYSTROPHY, POSTERIOR POLYMORPHOUS, 1, PPCD, CORNEAL ENDOTHELIAL DYSTROPHY 1, AUTOSOMAL DOMINANT, FORMERLY 
This corneal dystrophy affects the posterior limiting membrane of the cornea and is characterized by polymorphous plaques of calcium deposits in the… (More)
National Institutes of Health

Related topics

Related topics

5 relations
Autosomal dominant inheritanceCOL8A2 geneCORNEAL ENDOTHELIAL DYSTROPHY 2Secondary glaucoma

Broader (1)

Hereditary corneal dystrophy

Papers overview

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2017
2017
Transcriptomic Profiling of Posterior Polymorphous Corneal Dystrophy
Purpose To investigate the molecular basis of posterior polymorphous corneal dystrophy (PPCD) by examining the PPCD transcriptome… (More)
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Highly Cited
2010
Highly Cited
2010
Missense mutations in TCF8 cause late-onset Fuchs corneal dystrophy and interact with FCD4 on chromosome 9p.
Fuchs corneal dystrophy (FCD) is a degenerative genetic disorder of the corneal endothelium that represents one of the most… (More)
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Highly Cited
2008
Highly Cited
2008
SLC4A11 mutations in Fuchs endothelial corneal dystrophy.
The endothelial (posterior) corneal dystrophies, which result from primary endothelial dysfunction, include Fuchs endothelial… (More)
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2008
2008
Analysis of the posterior polymorphous corneal dystrophy 3 gene, TCF8, in late-onset Fuchs endothelial corneal dystrophy.
PURPOSE Because the endothelial (posterior) corneal dystrophies share common pathologic features and result from primary… (More)
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2007
2007
Posterior polymorphous corneal dystrophy is associated with TCF8 gene mutations and abdominal hernia.
Mutations in the two-handed zinc-finger homeodomain transcription factor gene (TCF8) have been associated with posterior… (More)
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2007
2007
Replication and refinement of linkage of posterior polymorphous corneal dystrophy to the posterior polymorphous corneal dystrophy 1 locus on chromosome 20
Purpose: The study purpose was to identify the genetic basis of posterior polymorphous corneal dystrophy, an autosomal dominant… (More)
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Highly Cited
2005
Highly Cited
2005
Mutations in TCF8 cause posterior polymorphous corneal dystrophy and ectopic expression of COL4A3 by corneal endothelial cells.
Posterior polymorphous corneal dystrophy (PPCD, also known as PPMD) is a rare disease involving metaplasia and overgrowth of… (More)
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2005
2005
Posterior polymorphous corneal dystrophy in Czech families maps to chromosome 20 and excludes the VSX1 gene.
PURPOSE Posterior polymorphous corneal dystrophy (PPCD) is an autosomal dominant disorder, affecting both the corneal endothelium… (More)
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Highly Cited
1995
Highly Cited
1995
Linkage of posterior polymorphous corneal dystrophy to 20q11.
Posterior polymorphous dystrophy (PPMD) is an autosomal dominant disorder of the cornea that is clinically recognized by the… (More)
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1989
1989
Four cases of keratoconus and posterior polymorphous corneal dystrophy.
We examined four young men with keratoconus and posterior polymorphous corneal dystrophy. All four patients showed central… (More)
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