FAQ

Poly(A)-Binding Protein II

Known as: Poly(A) Binding Protein II, Pabp2 Protein, Poly(A)-Binding Protein II [Chemical/Ingredient] 
A poly(A) binding protein that is involved in promoting the extension of the poly A tails of MRNA. The protein requires a minimum of ten ADENOSINE… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2013
01219932013

Related topics

Related topics

13 relations
In BloodMuscular Dystrophy, OculopharyngealPABPC1P2 genePABPN1 gene
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Poly(A)-Binding Protein II
physiological aspects
agonists
chemical synthesis
Muscular Dystrophy, Oculopharyngeal
standards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Heat shock 70 protein interaction with Turnip mosaic virus RNA-dependent RNA polymerase within virus-induced membrane vesicles.
Tandem affinity purification was used in Arabidopsis thaliana to identify cellular interactors of Turnip mosaic virus (TuMV) RNA… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2002
2002
Mammalian, yeast, bacterial, and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophy.
Autosomal dominant oculopharyngeal muscular dystrophy (OPMD) is characterized pathologically by intranuclear inclusions in… (More)
Is this relevant?
2001
2001
The product of an oculopharyngeal muscular dystrophy gene, poly(A)-binding protein 2, interacts with SKIP and stimulates muscle-specific gene expression.
Oculopharyngeal muscular dystrophy (OPMD) is caused by short expansions of the GCG trinucleotide repeat encoding the polyalanine… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Nuclear inclusions in oculopharyngeal muscular dystrophy consist of poly(A) binding protein 2 aggregates which sequester poly(A) RNA.
Oculopharyngeal muscular dystrophy (OPMD) is an adult-onset disease characterized by progressive eyelid drooping, swallowing… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
2000
2000
The nuclear poly(A) binding protein, PABP2, forms an oligomeric particle covering the length of the poly(A) tail.
The mammalian nuclear poly(A) binding protein, PABP2, controls the length of the newly synthesized poly(A) tail on messenger RNAs… (More)
Is this relevant?
2000
2000
Nuclear accumulation of expanded PABP2 gene product in oculopharyngeal muscular dystrophy.
Autosomal dominant oculopharyngeal muscular dystrophy (OPMD) is an adult-onset disease caused by (GCG) repeat expansions in exon… (More)
Is this relevant?
2000
2000
Deciphering the cellular pathway for transport of poly(A)-binding protein II.
Poly(A)-binding protein II (PABP2) is an abundant nuclear protein that binds with high affinity to nascent poly(A) tails… (More)
Is this relevant?
1995
1995
Poly(A) tail length control is caused by termination of processive synthesis.
  • Eva Wahle
  • The Journal of biological chemistry
  • 1995
Poly(A) polymerase synthesizes poly(A) tails rapidly and processively only when the substrate RNA is bound simultaneously by two… (More)
Is this relevant?
1994
1994
Immunodetection of poly(A) binding protein II in the cell nucleus.
During the polyadenylation of pre-mRNA in vitro, poly(A) binding protein II (PAB II) binds to the growing poly(A) tail… (More)
  • figure 1
  • figure 4
  • table 1
Is this relevant?
1993
1993
Assembly of a processive messenger RNA polyadenylation complex.
Polyadenylation of mRNA precursors by poly(A) polymerase depends on two specificity factors and their recognition sequences… (More)
Is this relevant?