Polar surface area

Known as: PSA, Topological Polar Surface Area 
The polar surface area (PSA) of a molecule is defined as the surface sum over all polar atoms, primarily oxygen and nitrogen, also including their… (More)
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Papers overview

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Highly Cited
2015
Highly Cited
2015
Therapeutic prostate-specific antigen (PSA) -targeted poxviral vaccines for prostate cancer have been well tolerated. PROSTVAC-VF… (More)
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2012
2012
A correlation has been established between the absorbed fraction of training-set molecules after oral administration in humans… (More)
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Highly Cited
2011
Highly Cited
2011
The subventricular zone of many adult non-human mammals generates large numbers of new neurons destined for the olfactory bulb… (More)
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Highly Cited
2010
Highly Cited
2010
Recent insights into the regulation of the androgen receptor (AR) activity led to novel therapeutic targeting of AR function in… (More)
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Highly Cited
2008
Highly Cited
2008
This paper contains ground-motion prediction equations (GMPEs) for average horizontal-component ground motions as a function of… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVES Men with elevated serum prostate-specific antigen (PSA) levels and negative prostate biopsy findings present a dilemma… (More)
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2000
2000
Modeling of the calculated polar surface area of drugs with rapidly derived descriptors (i.e., the number of hydrogen bonds… (More)
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Highly Cited
2000
Highly Cited
2000
The present study was undertaken to evaluate the prognostic significance of the serum levels of interleukin 6 (IL-6) in patients… (More)
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Highly Cited
1997
Highly Cited
1997
Prostate-specific antigen (PSA) is a widely used marker for the diagnosis and management of prostate cancer. Minimal enhancer… (More)
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Highly Cited
1996
Highly Cited
1996
Progression to androgen-independent growth of human prostate cancers may be mediated by alterations in the structure and/or… (More)
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