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Plexin Domain-Containing Protein 1

Known as: PLXDC1, Tumor Endothelial Marker 3, Tumor Endothelial Marker 7 
Plexin domain-containing protein 1 (500 aa, ~56 kDa) is encoded by the human PLXDC1 gene. This protein is involved in endothelial tube formation.
National Institutes of Health

Related topics

Related topics

4 relations
Genes, RegulatorPLXDC1 genePlasma membranePositive Regulation of Angiogenesis

Papers overview

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Highly Cited
2018
Highly Cited
2018
Selective delivery of PLXDC1 small interfering RNA to endothelial cells for anti-angiogenesis tumor therapy using CD44-targeted chitosan nanoparticles for epithelial ovarian cancer
Abstract Angiogenesis plays an essential role in the growth and metastasis of tumor cells, and the modulation of angiogenesis can… 
2017
2017
Abstract 2183: Targeted delivery of hyaluronic acid-labeled chitosan nanoparticles against CD44 overexpressed endothelial cell for tumor angiogenesis therapy
Objective: RNA interference (RNAi)-based approaches hold great potential for cancer therapy. Here, we developed siRNA… 
2015
2015
TEM 7 ( PLXDC 1 ) , a key prognostic predictor for resectable gastric cancer , promotes cancer cell migration and invasion
Tumor endothelial marker 7 (TEM7) is a new candidate of molecular target for antiangiogenic therapy. This study aims to evaluate… 
2015
2015
Original Article TEM7 (PLXDC1), a key prognostic predictor for resectable gastric cancer, promotes cancer cell migration and invasion
* Equal contributors. Received November 2, 2014; Accepted January 5, 2015; Epub January 15, 2015; Published February 1, 2015… 
Highly Cited
2010
Highly Cited
2010
Targeted Gene Silencing Using RGD-Labeled Chitosan Nanoparticles
Purpose: This study aimed to develop an Arg-Gly-Asp (RGD) peptide-labeled chitosan nanoparticle (RGD-CH-NP) as a novel tumor… 
2008
2008
TEM7 (PLXDC1) in neovascular endothelial cells of fibrovascular membranes from patients with proliferative diabetic retinopathy.
PURPOSE Proliferative diabetic retinopathy (PDR) results from the formation of fibrovascular membranes (FVMs) in the posterior… 
Highly Cited
2007
Highly Cited
2007
Nidogen is a prosurvival and promigratory factor for adult Schwann cells
Schwann cells provide a favorable microenvironment for successful regeneration of the injured peripheral nerve. Even though the… 
2006
2006
Expression of tumor endothelial marker 7 mRNA and protein in the dorsal root ganglion neurons of the rat
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