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Pizotyline

Known as: Pizotifen, Piperidine, 4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methyl-, 4-(9,10-Dihydro-4H-Benzo(4,5)Cyclohepta(1,2-B)Thien-4-ylidene)-1-Methylpiperidine 
Serotonin antagonist used against MIGRAINE DISORDERS and vascular headaches.
National Institutes of Health

Related topics

Related topics

13 relations

Broader (3)

Analgesics, Non-NarcoticAntidepressive AgentsSerotonin Antagonists

Narrower (3)

BC-105PolomigranSandomigran
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1997
1997
Lack of Interaction Between Pizotifen and the Novel Antimigraine Compound Zolmitriptan in Healthy Volunteers
SummaryThis double-blind, randomised, two-period crossover study investigated the effect of pizotifen on the pharmacokinetics and… 
1986
1986
Pizotifen, an antimigraine drug with venoconstrictor activity in vivo.
Determination of the diameter of saphenous veins in conscious dogs revealed a considerable agonist activity of pizotifen not only… 
1985
1985
Long-term effect of pizotifen treatment on growth hormone levels of underweight children, including those with anorexia nervosa.
Eight underweight children, 3 of them with anorexia nervosa, were treated for 3 months without interruption with 1.0 to 1.5 mg… 
1984
1984
Inhibition of 5-hydroxytryptamine-potentiated aggregation of human blood platelets by 5-hydroxytryptamine receptor-blocking agents.
Blood platelets possess specific receptors for 5-hydroxytryptamine (5-HT) which differ from the carrier for the amine uptake… 
1984
1984
The effect of pizotifen, a serotonin antagonist, and of pirenzepine, a muscarinic antagonist, on hormonal responses to metoclopramide in healthy subjects.
To examine whether and how muscarinic or serotoninergic properties might contribute to the hormone stimulating action of the… 
1983
1983
The effects of clonidine on electrically-induced contractions of rat detrusor strips in vitro.
Clonidine (10(-9)-3 X 10(-6) M) produced a concentration dependent inhibition of field stimulation-induced contractions of rat… 
1982
1982
Pizotifen in the treatment of severe recurrent headache single and divided dose therapy compared.
1980
1980
The effect of thyroliberin and some of its analogues on the hind limb flexor reflex in the spinal rat.
Thyroliberin (TRH) (0.5-4 mg/kg) enhanced the flexor reflex (increase in the reflex amplitude) in a dose-dependent way. A similar… 
1977
1977
Pizotifen in the treatment of migraine.
1975
1975
AN UNEXPECTED EFFECT OF SEROTONIN ANTAGONISTS ON THE CANINE NASAL CIRCULATION
SYNOPSIS