Pipemidic Acid

Known as: Piperamic Acid, Pyrido(2,3-d)pyrimidine-6-carboxylic acid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)-, Pipemidic Acid [Chemical/Ingredient] 
A pyridopyrimidine antibiotic derivative of piromidic acid with activity against gram-negative bacteria, as well as some gram-positive bacteria… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1974-2016
0102019742016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Autotaxin (ATX, NPP2) has recently been shown to be the lysophospholipase D responsible for synthesis of the bioactive lipid… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Genome studies suggest that DNA gyrase is the sole type II topoisomerase and likely the unique target of quinolones in… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
1995
1995
Quinolone antibiotics are extensively utilized in antimicrobial chemotherapy. However, quinolone treatment in developing… (More)
Is this relevant?
1990
1990
In order to evaluate the efficacy and safety of fosfomycin trometamol as single dose oral treatment for acute cystitis in women… (More)
Is this relevant?
1989
1989
Binding of cinoxain (CINX), nalidixic acid (NA) and pipemidic acid (PPA) to serum proteins was investigated by equilibrium… (More)
Is this relevant?
1989
1989
The relationship between the chemical structure and epileptogenic activity of quinolones was investigated. When the quinolones… (More)
  • figure 1
  • table 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
1984
1984
The in vitro activities of five quinolinecarboxylic acids against two laboratory strains of Chlamydia trachomatis were compared… (More)
  • table 1
  • table 2
Is this relevant?
1983
1983
An agar dilution method was used to measure the minimal inhibitory concentrations of ciprofloxacin (Bay o 9867), norfloxacin… (More)
  • table 1
Is this relevant?
1978
1978
Pipemidic acid (PPA) orally given in a dose of 100 mg/kg/day or more was found to cause lame gait in immature beagle dogs of… (More)
Is this relevant?
1975
1975
Pipemidic acid was absorbed well by the oral route. Its peak levels in plasma ranged from 4 to 12 mug/ml at an oral dose of about… (More)
Is this relevant?