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Piclozotan

 
National Institutes of Health

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2 relations

Broader (2)

OxazepinesSerotonin 5-HT1 Receptor Agonists

Papers overview

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2010
2010
Effects of piclozotan (SUN N4057), a partial serotonin 1A receptor agonist, on motor complications induced by repeated administration of levodopa in parkinsonian rats.
Serotonin 1A receptor agonists have attracted much interest recently as potential therapeutic agents for levodopa-induced motor… Expand
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2009
2009
Population pharmacokinetics of the selective serotonin 5-HT1A receptor partial agonist piclozotan.
BACKGROUND/AIMS Serotonin (5-HT) and its receptors are known to play important roles in various physiological and… Expand
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2006
2006
Synthesis, SAR studies, and evaluation of 1,4-benzoxazepine derivatives as selective 5-HT1A receptor agonists with neuroprotective effect: Discovery of Piclozotan.
A new series of 1,4-benzoxazepine derivatives was designed, synthesized, and evaluated for binding to 5-HT1A receptor and… Expand
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2006
2006
Other Neuroprotective Therapies on Trial in Acute Stroke
New neuroprotective agents on trial may potentially offer benefit to stroke patients without the associated hemorrhagic risk of… Expand
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2005
2005
Piclozotan (SUN N4057), a Novel 5HT1A Receptor Agonist, Is Well Tolerated in Patients with Acute Stroke
 
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