Phosphoserine aminotransferase

Known as: 3-phosphoserine oxoglutarate transaminase, Phosphohydroxythreonine Aminotransferase, 3-phosphoserine aminotransferase 
Phosphoserine aminotransferase (370 aa, ~40 kDa) is encoded by the human PSAT1 gene. This protein is involved in amino acid biosynthesis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1956-2017
051019562016

Related topics

Related topics

6 relations
Amino Acid BiosynthesisCytoplasmic matrixEnzyme GeneGlycine, Serine and Threonine Metabolism Pathway
(More)

Broader (1)

Transaminases

Related mentions per year

Related mentions per year

1945-2019
19401960198020002020
Phosphoserine aminotransferase
Transaminases
Cytoplasmic matrix
Amino Acid Biosynthesis
PSAT1 gene
Glycine, Serine and Threonine Metabolism Pathway

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells
Colorectal cancer (CRC) is one of the most common causes of cancer death throughout the world. In this work our aim was to study… (More)
  • table 1
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Association of DNA methylation of phosphoserine aminotransferase with response to endocrine therapy in patients with recurrent breast cancer.
To understand the biological basis of resistance to endocrine therapy is of utmost importance in patients with steroid hormone… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2005
Highly Cited
2005
RNA-dependent cysteine biosynthesis in archaea.
Several methanogenic archaea lack cysteinyl-transfer RNA (tRNA) synthetase (CysRS), the essential enzyme that provides Cys-tRNA… (More)
Is this relevant?
2005
2005
Enzyme adaptation to alkaline pH: atomic resolution (1.08 A) structure of phosphoserine aminotransferase from Bacillus alcalophilus.
The crystal structure of the vitamin B(6)-dependent enzyme phosphoserine aminotransferase from the obligatory alkaliphile… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
14-3-3ε is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller–Dieker syndrome
Heterozygous deletions of 17p13.3 result in the human neuronal migration disorders isolated lissencephaly sequence (ILS) and the… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
2003
2003
Characterization of human phosphoserine aminotransferase involved in the phosphorylated pathway of L-serine biosynthesis.
In the present study, we first report two forms of human phosphoserine aminotransferase (PSAT) cDNA (HsPSAT alpha and HsPSAT beta… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
1999
1999
Phosphoserine aminotransferase, the second step-catalyzing enzyme for serine biosynthesis.
As a step toward analyzing the serine biosynthetic pathway in mammals, we have studied the properties of phosphoserine… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Glutamate release in experimental ischaemia of the retina: an approach using microdialysis.
A rabbit eye model of neural ischaemia is described that uses an increased pressure in the anterior eye chamber to block the… (More)
Is this relevant?
1986
1986
Phosphoserine aminotransferase in soybean root nodules : demonstration and localization.
Phosphoserine aminotransferase activity was detected in the plant and bacteroid fractions from soybean (Glycine max) root nodules… (More)
Is this relevant?
1967
1967
Studies on phosphoserine aminotransferase of sheep brain.
Phosphoserine aminotransferase has been purified about 500-fold from sheep brain extracts by ammonium sulfate precipitation and… (More)
  • figure 1
  • figure 4
  • figure 2
  • figure 5
  • figure 3
Is this relevant?