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Phospholipase C gamma

Known as: Phosphoinositide Phospholipase C-Gamma, PLC-gamma, PLCgamma 
A phosphoinositide phospholipase C subtype that is primarily regulated by PROTEIN-TYROSINE KINASES. It is structurally related to PHOSPHOLIPASE C… 
National Institutes of Health

Related topics

Related topics

13 relations
In BloodPhospholipaseProcess of secretionantagonists & inhibitors

Narrower (5)

Phospholipase C gamma 2Phospholipase C gamma DPhospholipase C gamma1Plcg1 protein, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2005
Review
2005
Compartmentalized signalling of Ras.
Ras proteins associate with cellular membranes by virtue of a series of post-translational modifications of their C-terminal CAAX… 
Highly Cited
2004
Highly Cited
2004
DU145 human prostate carcinoma invasiveness is modulated by urokinase receptor (uPAR) downstream of epidermal growth factor receptor (EGFR) signaling.
Highly Cited
2003
Highly Cited
2003
Teleost fish spermatozoa contain a cytosolic protein factor that induces calcium release in sea urchin egg homogenates and triggers calcium oscillations when injected into mouse oocytes.
Highly Cited
2002
Highly Cited
2002
Src kinase induces calcium release in Xenopus egg extracts via PLCgamma and IP3-dependent mechanism.
Highly Cited
2001
Highly Cited
2001
Vav1 Regulates Phospholipase Cγ Activation and Calcium Responses in Mast Cells
ABSTRACT The hematopoietic cell-specific protein Vav1 is a substrate of tyrosine kinases activated following engagement of many… 
Highly Cited
2001
Highly Cited
2001
Membrane Raft Association of CD47 Is Necessary for Actin Polymerization and Protein Kinase C θ Translocation in Its Synergistic Activation of T Cells*
CD47 is a ubiquitously expressed membrane protein with an extracellular Ig domain and a multiple membrane-spanning domain that… 
Highly Cited
1999
Highly Cited
1999
Role of phospholipase Cgamma at fertilization and during mitosis in sea urchin eggs and embryos.
It is well known that stimulation of egg metabolism after fertilization is due to a rise in intracellular free calcium… 
Highly Cited
1997
Highly Cited
1997
Molecular inhibition of phospholipase cgamma signaling abrogates DU-145 prostate tumor cell invasion.
Up-regulated signaling from the epidermal growth factor receptor (EGFR) has been correlated with tumor invasion and metastasis in… 
1994
1994
Collagen stimulates tyrosine phosphorylation of phospholipase C-gamma 2 but not phospholipase C-gamma 1 in human platelets.
Collagen is an important primary stimulus of platelets during the process of hemostasis. As with many other platelet stimuli… 
Highly Cited
1989
Highly Cited
1989
Phosphorylation of phospholipase C-gamma by cAMP-dependent protein kinase.
The mechanism by which cAMP modulates the activity of phosphoinositide-specific phospholipase C (PLC) was studied. Elevation of… 
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