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Phortress

National Institutes of Health

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Thiazoles

Papers overview

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2012
2012
Chemistry of the Putative Metabolite of a Model Anti-tumor Drug
CHEMISTRY OF THE PUTATIVE METABOLITE OF A MODEL ANTI-TUMOR DRUG by Mrinal Chakraborty 2-(4-Aminophenyl)benzothiazoles related to… 
2010
2010
Phortress: the smart antitumour agent which induces its own metabolism
Phortress is the result of multidisciplinary research involving pharmacists, chemists, molecular biologists, pharmacologists and… 
2009
2009
Abstract B59: Preliminary clinical experiences of Phortress: Putative role for c‐MET inhibition in antitumor activity
Experimental antitumor agent Phortress elicits selective activity in vitro and in vivo in human breast, ovarian and renal… 
2008
2008
Preclinical Toxicokinetic Evaluation of Phortress [2-(4-Amino-3-Methylphenyl)-5-Fluorobenzothiazole Lysylamide Dihydrochloride] in Two Rodent Species
Background and Aims: The 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole prodrug Phortress exerts potent and selective… 
2006
2006
In vitro cytotoxicity of Phortress against colorectal cancer.
Phortress is a novel benzothiazole compound with activity concentrated in certain breast, ovarian and renal cancer cell lines… 
2004
2004
The Experimental Antitumor Agents Phortress and Doxorubicin are Equiactive Against Human-Derived Breast Carcinoma Xenograft Models
Phortress (the dihydrochloride salt of the lysylamide prodrug of 2-(4-amino-3-methylphenyl)-5-fluoro-benzothiazole (5F 203)) is… 
2003
2003
Antitumour benzothiazoles : analysis of DNA damage induced by Phortress.
2002
2002
The development of Phortress : from molecule to mechanism.
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