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Phase I Clinical Trials

Known as: Trial Phase 1, phase i clinical trial, Clinical Trials, Phase I 
Works about studies performed to evaluate the safety of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques in healthy subjects… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Zika virus (ZIKV), a mosquito-borne flavivirus, was first identified in the 1940s in Uganda in Africa and emerged in the Americas… Expand
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Highly Cited
2016
Highly Cited
2016
SummaryPurpose Naturally occurring tumor suppressor microRNA-34a (miR-34a) downregulates the expression of >30 oncogenes across… Expand
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Highly Cited
2016
Highly Cited
2016
Osteoarthritis (OA) is the most widespread musculoskeletal disorder in adults. It leads to cartilage damage associated with… Expand
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2016
2016
Transmembrane glycoprotein CD44 is overexpressed in various malignancies. Interactions between CD44 and hyaluronic acid are… Expand
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Highly Cited
2015
Highly Cited
2015
AFM13 is a bispecific, tetravalent chimeric antibody construct (TandAb) designed for the treatment of CD30-expressing… Expand
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Highly Cited
2015
Highly Cited
2015
We carried out a multicenter dose‐escalation phase I study of oral OPB‐51602, a signal transducer and activator of transcription… Expand
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Highly Cited
2014
Highly Cited
2014
Sepsis is a massive inflammatory response mediated by infection, characterized by oxidative stress, release of cytokines, and… Expand
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Highly Cited
2004
Highly Cited
2004
Purpose: The 14 amino acid sequence (aa450–463) TKDNNLLGRFELSG (TKD) of heat shock protein 70 (Hsp70) was identified as a tumor… Expand
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Highly Cited
1999
Highly Cited
1999
OBJECTIVE To investigate the growth of interest, if any, in complementary or alternative medicine by the professional scientific… Expand
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Highly Cited
1990
Highly Cited
1990
This paper looks at a new approach to the design and analysis of Phase 1 clinical trials in cancer. The basic idea and motivation… Expand
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