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Phagolysosomes

Known as: Phagolysosome 
A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis… 
National Institutes of Health

Related topics

Related topics

3 relations
Cytoplasm

Broader (1)

Phagosomes

Narrower (1)

phagolysosome membrane

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis
Significance Phagocytes are key to innate immunity, as they ingest, kill, and degrade foreign particles, such as microbes… 
Highly Cited
2004
Highly Cited
2004
Factors affecting the escape of Francisella tularensis from the phagolysosome.
The highly virulent bacterium Francisella tularensis is well adapted to the intracellular habitat but the mechanisms behind its… 
Highly Cited
2004
Highly Cited
2004
On phagosome individuality and membrane signalling networks.
Highly Cited
2003
Highly Cited
2003
Signal sequence within FcγRIIA controls calcium wave propagation patterns: Apparent role in phagolysosome fusion
Calcium oscillations and traveling calcium waves have been observed in living cells, although amino acid sequences regulating… 
Review
2001
Review
2001
Evasion of host cell defense mechanisms by pathogenic bacteria.
Highly Cited
1995
Highly Cited
1995
Phagocytic processing of antigens for presentation by MHC molecules.
Highly Cited
1992
Highly Cited
1992
Phagolysosomes of Coxiella burnetii-infected cell lines maintain an acidic pH during persistent infection
Coxiella burnetii, the agent of Q fever, is an obligate intracellular bacterium that multiples within vacuoles of phagolysosomal… 
Highly Cited
1992
Highly Cited
1992
Recombinant Escherichia coli express a defined, cytoplasmic epitope that is efficiently processed in macrophage phagolysosomes for class II MHC presentation to T lymphocytes.
Although the processing of soluble Ag for presentation to T cells has been extensively studied in vitro, similar studies of… 
Highly Cited
1990
Highly Cited
1990
The major surface glycoprotein (GP63) is present in both life stages of Leishmania.
Highly Cited
1981
Highly Cited
1981
Inhibition of phagolysosome fusion is localized to Chlamydia psittaci-laden vacuoles
Intracellular survival of Chlamydia psittaci is in part dependent on the ability of the organism to thwart phagolysosome… 
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