Phagolysosomes

Known as: Phagolysosome 
A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
M. tuberculosis and M. leprae are considered to be prototypical intracellular pathogens that have evolved strategies to enable… (More)
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Review
2007
Review
2007
Leishmania amastigotes primarily proliferate within macrophages in the mammalian host. Genome-based metabolic reconstructions… (More)
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Highly Cited
2006
Highly Cited
2006
Infection of mammalian hosts with Leishmania amazonensis depends on the remarkable ability of these parasites to replicate within… (More)
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Highly Cited
2004
Highly Cited
2004
Mycobacterium tuberculosis is an intracellular pathogen persisting within phagosomes through interference with phagolysosome… (More)
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Highly Cited
2004
Highly Cited
2004
The highly virulent bacterium Francisella tularensis is well adapted to the intracellular habitat but the mechanisms behind its… (More)
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Highly Cited
2001
Highly Cited
2001
Cathelicidins are a family of antimicrobial proteins found in the peroxidase-negative granules of neutrophils. The known biologic… (More)
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Highly Cited
2001
Highly Cited
2001
Phagosomes are key organelles for the innate ability of macrophages to participate in tissue remodeling, clear apoptotic cells… (More)
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Highly Cited
1999
Highly Cited
1999
Recently, we demonstrated that human monocyte-derived macrophages (MDM) treated with chloroquine or ammonium chloride had… (More)
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Highly Cited
1994
Highly Cited
1994
We have examined the modifications occurring during the transformation of phagosomes into phagolysosomes in J-774 macrophages… (More)
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Highly Cited
1993
Highly Cited
1993
The phagolysosome is perhaps the most effective antimicrobial site within macrophages due both to its acidity and to its variety… (More)
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