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Ph-Like Acute Lymphoblastic Leukemia

Known as: Ph-Like, Ph-Like ALL 
A leukemia subtype characterized by a gene-expression profile similar to that of BCR-ABL1-positive acute lymphoblastic leukemia, alterations of… 
National Institutes of Health

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13 relations
Atypical lymphocyteBone MarrowHematopoietic and Lymphoid CellHematopoietic and Lymphoid Tissue

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Use of microarrays and MLPA for integrating diagnostics and personalizing treatment - Case report of a patient with Ph-like acute B-cell lymphoblastic leukemia.
B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is the most common childhood cancer. A special subtype of high risk BCP… 
Review
2020
Review
2020
Blinatumomab in Ph-like Acute Lymphoblastic Leukemia – an Institutional Experience
2017
2017
[Screening of adult Ph-like acute lymphoblastic leukemia by multiplex real-time quantitative PCR].
  • M. Z. XuQ. Fang Y. Mi
  • Zhonghua xue ye xue za zhi = Zhonghua xueyexue…
  • 2017
  • Corpus ID: 9558973
Objective: To investigate the feasibility of multiplex real-time RT-PCR with fluorescent probes in early screening of Ph-like… 
2016
2016
Adaptive Reactivation of Signaling Pathways As a Novel Mechanism of Resistance to JAK Inhibitors in Ph-like ALL
Background : Ph-like ALL was first described in 2009 and was accepted as a novel B-ALL subgroup by the WHO in 2016. Ph-like ALL… 
2016
2016
High-Risk Subtype of Ph-like Acute Lymphoblastic Leukemia (ALL) in Adults: Dismal Outcomes of CRLF2+ ALL Patients Treated with Intensive Chemotherapy
Background: Ph-like acute lymphoblastic leukemia (ALL) is a high-risk subtype of ALL in children. There are limited and… 
2016
2016
In Vitro Modeling of Ph-like ALL Fusions Identifies Novel Kinase-Domain Mutations As Mode of TKI-Resistance - Implications for Targeted Therapy
Introduction Treatment-resistant acute lymphoblastic leukemia (ALL) remains a significant clinical issue. Recently, genomic… 
2015
2015
Potent Efficacy of Combined PI3K/mTOR and JAK or SRC/ABL Inhibition in Philadelphia Chromosome-like Acute Lymphoblastic Leukemia
Background. Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is associated with genomic alterations that… 
2015
2015
Abstract 4729: Frequency of actionable gene fusions in patients with Philadelphia chromosome-like (Ph-like) B-acute lymphoblastic leukemia (ALL): A retrospective study from the Children's Oncology…
Introduction: While cure rates exceed 80%, many children with B-ALL still relapse. Many of these patients (pts) display a Ph-like… 
2014
2014
Abstract 3083: The genetic landscape of Ph-like acute lymphoblastic leukemia
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA BCR-ABL1-like, or “Ph-like” B-progenitor acute… 
2013
2013
Therapy of pediatric ALL: from Bowie to Obama.
In this issue of Blood , van der Veer et al report that the Ph-like/BCR-ABL1-like phenotype and IKZF1 deletions, but not CRLF2… 
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