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Penbutolol

Known as: Penbutololum, 2-Propanol, 1-(2-cyclopentylphenoxy)-3-((1,1-dimethylethyl)amino)-, (S)-, (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol 
A lipophilic, nonselective beta-adrenergic receptor antagonist with anti-anginal and antihypertensive activities. Penbutolol competitively binds to… 
National Institutes of Health

Related topics

Related topics

26 relations

Narrower (3)

4-hydroxypenbutololBetapressinHoe-893d

Broader (2)

Adrenergic beta-AntagonistsAntihypertensive Agents
Angina PectorisArterial Vasodilation [PE]BradycardiaBronchial Hyperreactivity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Stereospecific high-performance liquid chromatographic analysis of tramadol and its O-demethylated (M1) and N,O-demethylated (M5) metabolites in human plasma.
2004
2004
Characteristics of photocatalytic oxidation of gaseous 2-propanol using thin-film TiO2 photocatalyst
This work presents a photocatalysis-based method to treat and purify air because of its broad applicability to common, oxidizable… 
Review
2002
Review
2002
Synthesis and evaluation of radiolabeled antagonists for imaging of β-adrenoceptors in the brain with PET
1996
1996
Solid-phase extraction and derivatisation methods for beta-blockers in human post mortem whole blood, urine and equine urine.
1994
1994
Effects of antiischemic drugs on veratridine-induced hypercontracture in rat cardiac myocytes.
1987
1987
The membrane stabilizing activity of beta-adrenoceptor ligands. Quantitative evaluation of the interaction of phenoxypropanolamines with the [3H]batrachotoxinin A 20-alpha-benzoate binding site on…
Review
1983
Review
1983
Effects of 10 Different β‐Adrenoceptor Antagonists on Hemodynamics, Plasma Renin Activity, and Plasma Norepinephrine in Hypertension: The Key Role of Vascular Resistance Changes in Relation to…
Summary The literature was surveyed for the acute and long-term hemodynamic effects of 10 different β-adrenoceptor antagonists… 
1977
1977
Comparative beta-adrenoceptor blocking effects and pharmacokinetics of penbutolol and propranolol in man.
1 The beta-adrenoceptor blocking effects of penbutolol were compared with those of propranolol and a placebo in a double-blind… 
Highly Cited
1975
Highly Cited
1975
The effect of clonidine and penbutolol, respectively on catecholamines in blood and urine, plasma renin activity and urinary aldosterone in hypertensive patients.
In various kinds of hypertension clonidine induced a decrease in urinary catecholamines, plasma renin activity and urinary… 
1975
1975
Long term treatment of moderate hypertension with penbutolol (Hoe 893d). I. Effects on blood pressure, pulse rate, catecholamines in blood and urine, plasma renin activity and urinary aldosterone…
SummaryThe effects of penbutolol (Hoe 893 d), a new non-selective beta-receptor blocking agent, were studied in 5 patients with… 
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