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Fluoroquinolones have been the centre of considerable scientific and clinical interest due to their broad spectrum… Expand The antibiotic type organic structure pefloxacin binds well with europium (III) ions as a useful scaffold for assembling optical… Expand Pefloxacin (PFL) is a fluoroquinolone with a broad spectrum of antimicrobial activity against both Gram-negative and Grampositive… Expand The interaction of pefloxacin(PEF)-Al(Ⅲ) complex with DNA was studied by fluorescence and UV spectrametric methods.The spectral… Expand SummaryThis investigation focused on the labeling of pefloxacin, a fluoroquinolone antibacterial agent, with 99mTc to form 99mTc… Expand The complex of pefloxacin-La3+ was formed in the pH 5.6 HAc-NaAc buffer. Its fluorimetric intensity was 1.5 times that of the… Expand Pefloxacin is reported to cause clinically relevant inhibition of theophylline metabolism in vivo, but in vitro pefloxacin was… Expand BACKGROUND
Pefloxacin, a fluorinated 4-quinolone, has recently been advocated as a first-line treatment for minimal-change… Expand The disposition of ciprofloxacin and pefloxacin in the rat cerebrospinal fluid (CSF) was investigated after i.v. and i.c.v… Expand Multiple-dose kinetics of pefloxacin was determined in 12 normal male subjects given 400 mg pefloxacin by iv 1 h-infusion every… Expand