Pediatric Intraocular Retinoblastoma

OBJECTIVE To determine whether intra-arterial chemotherapy is safe and effective in advanced intraocular retinoblastoma… (More)

PURPOSE To identify the maximum tolerated dose and dose-limiting toxicity of periocular topotecan in patients with relapsed or… (More)

Recently, there has been increasing interest in treating intraocular retinoblastoma with systemic chemotherapy combined with… (More)

PURPOSE To evaluate the efficacy of chemoreduction using vincristine and carboplatin in preventing or delaying external-beam… (More)

PURPOSE To study the effectiveness of combined systemic chemotherapy and local ophthalmic therapy for retinoblastoma with the… (More)

PURPOSE To evaluate the efficacy and toxicity of subconjunctival carboplatin for intraocular retinoblastoma. DESIGN A phase I… (More)

OBJECTIVE The purpose of the study is to investigate chemoreduction and adjuvant treatment (AT) for retinoblastoma and its effect… (More)

BACKGROUND External beam radiotherapy is standard treatment for medium and large, or visually threatening, intraocular… (More)

BACKGROUND Chemoreduction is a method of reducing tumor volume to allow for more focused, less damaging therapeutic measures… (More)

Chemotherapy without radiation has not controlled most intraocular retinoblastoma, perhaps because of the common high expression… (More)