Pathologic Mutagenesis

Known as: Mutagenic Process, Mutagenic Process, Pathologic 
Any event, process, or activity that produces a deleterious alteration of DNA. (NCI)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2017
02419912017

Papers overview

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2015
2015
Aristolochic acid (AA) is a potent dietary cytotoxin and carcinogen, and an established etiological agent underlying severe human… (More)
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2015
2015
DNA polymerases incorporate ribonucleoside monophosphates (rNMPs) into genomic DNA at a low level and such rNMPs are efficiently… (More)
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2011
2011
In recent years, it has been proposed that conflicts between transcription and active chromosomal replication engender genome… (More)
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2008
2008
With the goal of understanding the role of non-homologous end-joining repair in the maintenance of genetic information at the… (More)
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2005
2005
Proper repair of DNA double-strand breaks (DSBs) is necessary for the maintenance of genomic integrity. Here, a new simple assay… (More)
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2003
2003
Resting cells experience mutations without apparent external mutagenic influences. Such DNA replication-independent mutations are… (More)
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2000
2000
A novel method for monitoring of mutagenic process of dimethyl sulfate to Salmonella typhimurium strain (TA100) was proposed by… (More)
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1999
1999
The Escherichia coli umuDC operon is induced in response to replication-blocking DNA lesions as part of the SOS response. UmuD… (More)
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1998
1998
Oxidative damage of DNA by endogenously generated oxygen radicals contributes to the mutagenic process. Hydroxy, alkoxy, and… (More)
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Highly Cited
1991
Highly Cited
1991
The p53 gene has been implicated as a tumor-suppressor gene whose disruption is involved in the pathogenesis of common human… (More)
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