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Patched-1 Receptor

Known as: Patched 1 Receptor, Patched Receptor 1, Patched Homolog-1 
A patched receptor for several HEDGEHOG PROTEINS that associates with the SMOOTHENED RECEPTOR to modulate hedgehog signaling. It is also a TUMOR… 
National Institutes of Health

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In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

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PTCH protein, humanptch1 protein, zebrafish

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The Expression of Shh, Ptch1, and Gli1 in the Developing Caudal Spinal Cord of Fetal Rats With Anorectal Malformations.
2015
2015
Hedgehog Signaling Modulates the Release of Gliotransmitters from Cultured Cerebellar Astrocytes
Sonichedgehog (Shh), a member of the Hedgehog (Hh) family, plays essential roles in the development of the central nervous system… 
2015
2015
Sclerosing Basal Cell Carcinoma
An 85-year-old Caucasian man presented with a slowly growing, asymptomatic, linear, scar-like lesion just above the right… 
2014
2014
Hedgehog-glioma-associated oncogene homolog-1 signaling in colon cancer cells and its role in the celecoxib-mediated anti-cancer effect
Hedgehog (Hh) signaling is activated in numerous malignant tumors, but its role in human colorectal cancer remains uncertain… 
2013
2013
A non‐coding mutation in the 5′ untranslated region of patched homologue 1 predisposes to basal cell carcinoma
Mutations in the human homolog of the Drosophila patched gene, patched homologue 1 (PTCH‐1), are responsible for most hereditary… 
2011
2011
PTCH1 gene inactivation is not a Keratocystic odontogenic tumour exclusive alteration.
2006
2006
Brain- and heart-specific Patched-1 containing exon 12b is a dominant negative isoform and is expressed in medulloblastomas.
2004
2004
A novel first exon of the Patched1 gene is upregulated by Hedgehog signaling resulting in a protein with pathway inhibitory functions
2002
2002
Changes in the protein expression of hedgehog and patched-1 in perisutural tissues induced by cranial distraction.
With the modern emphasis on minimally invasive therapies, the concept of distraction is being applied in the treatment of… 
2002
2002
Comparison of hedgehog and patched-1 protein expression in the cranial sutures of craniosynostotic and wild-type rabbits.
Craniosynostosis is characterized by premature fusion of the cranial sutures. At the molecular level, mutations in homeobox genes… 
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