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Pargluva

National Institutes of Health

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muraglitazar

Papers overview

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2007
2007
Comparative Metabolism of Radiolabeled Muraglitazar in Animals and Humans by Quantitative and Qualitative Metabolite Profiling
Muraglitazar (Pargluva), a dual α/γ peroxisome proliferator-activated receptor (PPAR) activator, has both glucose- and lipid… 
2007
2007
Involvement of Multiple Cytochrome P450 and UDP-Glucuronosyltransferase Enzymes in the in Vitro Metabolism of Muraglitazar
Muraglitazar (Pargluva), a dual α/γ peroxisome proliferator-activated receptor activator, has both glucose- and lipid-lowering… 
2006
2006
STRUCTURAL ELUCIDATION OF HUMAN OXIDATIVE METABOLITES OF MURAGLITAZAR: USE OF MICROBIAL BIOREACTORS IN THE BIOSYNTHESIS OF METABOLITE STANDARDS
Muraglitazar (Pargluva), a dual α/γ peroxisome proliferator-activated receptor activator, is currently in clinical development… 
2006
2006
GLUCURONIDATION AS A MAJOR METABOLIC CLEARANCE PATHWAY OF 14C-LABELED MURAGLITAZAR IN HUMANS: METABOLIC PROFILES IN SUBJECTS WITH OR WITHOUT BILE COLLECTION
The metabolism and disposition of 14C-labeled muraglitazar (Pargluva), a novel dual α/γ peroxisome proliferator-activated… 
2006
2006
BIOTRANSFORMATION OF CARBON-14-LABELED MURAGLITAZAR IN MALE MICE: INTERSPECIES DIFFERENCE IN METABOLIC PATHWAYS LEADING TO UNIQUE METABOLITES
Muraglitazar (Pargluva; Bristol-Myers Squibb), a dual α/γ peroxisome proliferator-activated receptor activator, is under… 
2006
2006
GLUCURONIDATION AS A MAJOR METABOLIC CLEARANCE PATHWAY OF 14 C-LABELED MURAGLITAZAR IN HUMANS : METABOLIC PROFILES IN SUBJECTS WITH OR WITHOUT
The metabolism and disposition of C-labeled muraglitazar (Pargluva), a novel dual / peroxisome proliferator-activated receptor… 
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