Skip to search formSkip to main contentSkip to account menu

Panhypopituitarism

Known as: Combined pituitary hormone deficiency, Complete Hypopituitarism, primary hypopituitarism 
Insufficient production of all the anterior pituitary hormones.
National Institutes of Health

Related topics

Related topics

7 relations
CULLER-JONES SYNDROMEEndocrine System DiseasesEndocrine systemPallister-Hall syndrome

Broader (1)

Hypopituitarism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Genetic screening of combined pituitary hormone deficiency: experience in 195 patients.
CONTEXT Mutations in transcription factors result in combined pituitary hormone deficiency (CPHD). OBJECTIVE A genetic… 
Review
2001
Review
2001
POU domain factors in the neuroendocrine system: lessons from developmental biology provide insights into human disease.
POU domain factors are transcriptional regulators characterized by a highly conserved DNA-binding domain referred to as the POU… 
Highly Cited
2000
Highly Cited
2000
Mutations in LHX3 result in a new syndrome revealed by combined pituitary hormone deficiency
Combined pituitary hormone deficiency (CPHD) has been linked with rare abnormalities in genes encoding transcription factors… 
Highly Cited
1999
Highly Cited
1999
"Hot spot" in the PROP1 gene responsible for combined pituitary hormone deficiency.
As pituitary function depends on the integrity of the hypothalamic-pituitary axis, any defect in the development and… 
Highly Cited
1999
Highly Cited
1999
Longitudinal hormonal and pituitary imaging changes in two females with combined pituitary hormone deficiency due to deletion of A301,G302 in the PROP1 gene.
Genomic DNA from 18 patients with combined pituitary hormone deficiency was screened for 2-bp deletion (A301,G302) in PROP1 gene… 
Highly Cited
1998
Highly Cited
1998
Phenotypic variability in familial combined pituitary hormone deficiency caused by a PROP1 gene mutation resulting in the substitution of Arg-->Cys at codon 120 (R120C).
As pituitary function depends on the integrity of the hypothalamic-pituitary axis, any defect in the development and… 
Review
1994
Review
1994
Four varied cases of intravascular lymphomatosis and a literature review
Background. Intravascular lymphoma (IVL) is an uncommon malignancy defined pathologically by neoplastic proliferation of lymphoid… 
Highly Cited
1992
Highly Cited
1992
A Mutation in the POU-Homeodomain of Pit-1 Responsible for Combined Pituitary Hormone Deficiency
Pit-1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals… 
Highly Cited
1992
Highly Cited
1992
Mutations in the Pit-1 gene in children with combined pituitary hormone deficiency.
Highly Cited
1975
Highly Cited
1975
Hypopituitarism after external irradiation. Evidence for both hypothalamic and pituitary origin.
Endocrine complications after radiotherapy for tumors of the head and neck are thought to be relatively rare. The availability of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)