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PX20606

 
National Institutes of Health

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Topic mentions per year

2012-2017
01220122017

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2017
2017
The FXR agonist PX20606 ameliorates portal hypertension by targeting vascular remodelling and sinusoidal dysfunction.
BACKGROUND & AIMS Steroidal farnesoid X receptor (FXR) agonists demonstrated potent anti-fibrotic activities and lowered portal… (More)
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2017
2017
Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice.
BACKGROUND & AIMS The role of the intestine in the maintenance of cholesterol homeostasis increasingly is recognized. Fecal… (More)
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2015
2015
The nuclear bile acid receptor FXR controls the liver derived tumor suppressor histidine-rich glycoprotein.
The nuclear bile acid receptor Farnesoid X receptor (FXR) is strongly expressed in liver and intestine, controls bile acid and… (More)
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2012
2012
Synthetic farnesoid X receptor agonists induce high-density lipoprotein-mediated transhepatic cholesterol efflux in mice and monkeys and prevent atherosclerosis in cholesteryl ester transfer protein…
Farnesoid X receptor (FXR), a bile acid-activated nuclear hormone receptor, plays an important role in the regulation of… (More)
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