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PX20606

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Faculty of 1000 evaluation for The FXR agonist PX20606 ameliorates portal hypertension by targeting vascular remodelling and sinusoidal dysfunction.
Highly Cited
2017
Highly Cited
2017
The FXR agonist PX20606 ameliorates portal hypertension by targeting vascular remodelling and sinusoidal dysfunction.
Highly Cited
2017
Highly Cited
2017
Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice.
BACKGROUND & AIMS The role of the intestine in the maintenance of cholesterol homeostasis increasingly is recognized. Fecal… 
2016
2016
The non-steroidal FXR agonists PX20606 and GS-9674 improve liver fibrosis and portal hypertension in rodent models of cholestatic, metabolic and toxic liver cirrhosis
2015
2015
The nuclear bile acid receptor FXR controls the liver derived tumor suppressor histidine‐rich glycoprotein
The nuclear bile acid receptor Farnesoid X receptor (FXR) is strongly expressed in liver and intestine, controls bile acid and… 
2015
2015
The FXR agonist PX20606 reduces liver damage, fibrosis and portal hypertension in cirrhotic rats
2015
2015
P0271 : Effects of FXR agonist PX20606 on tumour formation in animal models of non-alcoholic fatty liver disease
2014
2014
P43 THE SYNTHETIC FXR AGONIST PX20606 ATTENUATES BACTERIAL TRANSLOCATION, INTESTINAL INFLAMMATION, AND REDUCES SPLANCHNIC BLOOD FLOW IN PORTAL HYPERTENSIVE MICE
Highly Cited
2012
Highly Cited
2012
Synthetic Farnesoid X Receptor Agonists Induce High-Density Lipoprotein-Mediated Transhepatic Cholesterol Efflux in Mice and Monkeys and Prevent Atherosclerosis in Cholesteryl Ester Transfer Protein…
Farnesoid X receptor (FXR), a bile acid-activated nuclear hormone receptor, plays an important role in the regulation of… 
2012
2012
Synthetic FXR agonist Px20606 lowers cholesterol in HDL2 but not in HDL3 subfractions and demonstrates anti-atherosclerotic effects
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