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National Institutes of Health
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Analysis of Biphenyl-Type Inhibitors Targeting the Eg5 α4/α6 Allosteric Pocket
Corpus ID: 51659513
Eg5 is a mitotic kinesin protein that plays an important role in the formation and maintenance of the bipolar spindle during the…
Structural basis of new allosteric inhibition in Kinesin spindle protein Eg5.
ACS chemical biology
Corpus ID: 25490171
Kinesin spindle protein Eg5 is a target for anticancer therapies, and small molecule inhibitors of its ATPase activity have been…
Bis(hetero)aryl derivatives as unique kinesin spindle protein inhibitors.
Bioorganic & medicinal chemistry letters
Corpus ID: 206239243
Synthesis of 4-(4-tert-butylphenyl)pyridine analogues as kinesin spindle protein (KSP) inhibitors, SAR, cytotoxicity and mitotic…
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