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PTU 23

Known as: PTU-23 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
A case report dysregulated neutrophil extracellular traps in a patient with propylthiouracil-induced anti-neutrophil cytoplasmic antibody-associated vasculitis
Rationale: Neutrophil extracellular traps (NETs) are immune defence systems that release extracellular chromatin and myeloid… 
2017
2017
The pattern of thalamocortical and brain stem projections to the vibrissae–related sensory and motor cortices in de-whiskered congenital hypothyroid rats
The present study is designed to investigate the plastic organization of the thalamo-cortical (TC) and brain stem afferents of… 
2005
2005
S-oxygenation of thiocarbamides I: Oxidation of phenylthiourea by chlorite in acidic media.
The oxidation of 1-phenyl-2-thiourea (PTU) by chlorite was studied in aqueous acidic media. The reaction is extremely complex… 
1996
1996
T cells ignore the parent drug propylthiouracil but are sensitized to a reactive metabolite generated in vivo.
The antithyroid drug propylthiouracil (PTU) is known to cause adverse immunological side effects, such as a lupus-like syndrome… 
1989
1989
Metabolism of 35S- and 14C-labeled propylthiouracil in a model in vitro system containing thyroid peroxidase.
In previous communications we described an in vitro model system containing highly purified thyroid peroxidase (TPO) for studying… 
Review
1982
Review
1982
Pharmacokinetics of antithyroid drugs
SummaryStudies of antithyroid drug pharmacokinetics suffer from the lack of simple and sensitive methods for the measurement of… 
1979
1979
Oxidative metabolites of [2-14C]propylthiouracil in rat thyroid.
The identities and relative amounts of the major metabolites in rat thyroids 6 h after the administration of [14C… 
1975
1975
Effect of frequency of administration on the accumulation and metabolism of (35S) propylthiouracil by the rat thyroid.
Repeated administration (every 8 h) of (35S) Propylthiouracil (PTU) resulted in gradual accumulation of unmetabolised PTU by the… 
1972
1972
Lack of positive correlation between adenyl cyclase activity and iodide transport in rat thyroids.
Adenyl cyclase activity was determined in 9000 X g pellets of thyroid homogenates from a) intact rats that received no medication… 
1970
1970
Autoradiography of tritiated thymidine labeled anterior pituitary cells in propylthiouracil treated rats.
Mature male rats weighing 190–230 g were treated for 3–24 days with 2.5 mg of propylthiouracil (PTU) ip every 12 hr. During the… 
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