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PTPRK gene

Known as: PTPRK, protein tyrosine phosphatase, receptor type K, PROTEIN-TYROSINE PHOSPHATASE, RECEPTOR-TYPE, KAPPA 
This gene is involved in receptor signaling, cell-cell contact and cell migration.
National Institutes of Health

Related topics

Related topics

10 relations
Cell Migration Inhibition functionCell-Cell Adhesion ProcessDephosphorylationHydrolysis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Abstract 3449: Tyrosine phosphatase activity is required for response to Src kinase inhibition in cholangiocarcinoma
Background: Cancer of the biliary tract, cholangiocarcinoma (CCA), is increasing in incidence and has limited treatment options… 
Review
2017
Review
2017
Monochromosomal Hybrids and Chromosome Transfer: A Functional Approach for Gene Identification.
Functional complementation of cellular defects has been a valuable approach for localizing causative genes to specific… 
2016
2016
Targeting RSPO3 Reduces Stem Cell Function in PTPRK-RSPO3 Colon Tumors.
Inhibition of RSPO3 induces differentiation of PTPRK-RSPO3 fusion-positive colon tumors. 
2013
2013
Smads expression is changed following receptor-like protein tyrosine phosphatase kappa (PTPRK) knockdown in prostate cancer cell
2011
2011
P2-05-05: Receptor-Like Protein Tyrosine Phosphatase Kappa (PTPRK) and Its Biological Role in Angiogenesis.
Introduction: Protein Tyrosine Phosphatases (PTPs) are known as signalling molecules which affect cell growth, differentiation… 
2011
2011
Epigenetic silencing of the receptor tyrosine phosphatase, PTPRK, located at the frequently deleted 6q22.33-q23.2 region, leads to tumor growth via the constitutive activation of STAT3 in nasal-type…
Abstract 1378 Tumorigenesis is a multi-step process and involves the silencing of tumor suppressor genes (TSGs) by genetic and/or… 
2010
2010
Abstract P2-07-08: Receptor Like Protein Tyrosin Phosphatases kappa (PTPRK), Its Pattern of Expression in Clinical Breast Cancer and Biological Impact on Breast Cancer Cells
Background: PTPs are signaling molecules which regulate cell growth, differentiation and oncogenic transformation. PTPRK… 
2009
2009
Protein-tyrosine phosphatase-kappa regulates CD4+ T cell development through ERK1/2-mediated signaling.
2007
2007
Del(6)(q22) and BCL6 Rearrangements in Primary Central Nervous System Lymphoma (PCNSL) Are Indicators of an Aggressive Clinical Course.
Purpose: Despite therapeutic advancements, biological markers that predict the natural history of primary central nervous system… 
1999
1999
Expression of a truncated receptor protein tyrosine phosphatase kappa in the brain of an adult transgenic mouse
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