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PTPN9 gene

Known as: PTPN9, PROTEIN-TYROSINE PHOSPHATASE, NONRECEPTOR-TYPE, 9, protein tyrosine phosphatase, non-receptor type 9 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Design, synthesis, biological evaluation and molecular dynamics simulation studies of (R)-5-methylthiazolidin-4-One derivatives as megakaryocyte protein tyrosine phosphatase 2 (PTP-MEG2) inhibitors…
Abstract PTP-MEG2 plays a significant role in insulin production and is able to enhance insulin signaling and improve insulin… 
2019
2019
A Dual-Band Dual-Antenna System with Common-Metal Rim for Smartphone Applications
A dual-antenna system operating at WIFI and GPS bands is proposed for common-metal rimmed smartphones applications. This dual… 
2017
2017
High-content hydrogen water-induced downregulation of miR-136 alleviates non-alcoholic fatty liver disease by regulating Nrf2 via targeting MEG3
Abstract This study was aimed to investigate the potential regulatory mechanism of high-content hydrogen water (HHW) in non… 
2017
2017
Synthesis, bioactivity, 3D-QSAR studies of novel dibenzofuran derivatives as PTP-MEG2 inhibitors
PTP-MEG2 plays a critical role in the diverse cell signalling processes, so targeting PTP-MEG2 is a promising strategy for… 
2016
2016
Virtual screening, optimization, and identification of a novel specific PTP-MEG2 Inhibitor with potential therapy for T2DM
Megakaryocyte protein tyrosine phosphatase 2 (PTP-MEG2) is a tyrosine phosphatase expressed in megakaryocytic cells, and causes… 
2015
2015
A novel C25 sterol peroxide from the endophytic fungus Phoma sp. EA-122
Abstract A novel C25 sterol peroxide, phomasterol A (1), together with two known compounds (2–3), was isolated from the… 
Highly Cited
2012
Highly Cited
2012
Exploration of α-aminophosphonate N-derivatives as novel, potent and selective inhibitors of protein tyrosine phosphatases.
2012
2012
A Highly Selective and Potent PTP-MEG 2 Inhibitor with Therapeutic Potential for Type 2 Diabetes
Protein tyrosine phosphatases (PTPs) constitute a large family of signaling enzymes that control the cellular levels of protein… 
2011
2011
Dinuclear copper complexes of organic claw: potent inhibition of protein tyrosine phosphatases.
2010
2010
Protein-tyrosine Phosphatase PTPN 9 Negatively Regulates ErbB 2 and Epidermal Growth Factor Receptor Signaling in Breast Cancer Cells *
ErbB family of the receptor protein-tyrosine kinase plays an important role in the progression of human cancers including breast… 
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