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PTPN5 gene

Known as: PTPSTEP, STEP, striatal-enriched protein tyrosine phosphatase 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Significance NMDA receptors (NMDARs) are principal regulators of synaptic signaling in the brain. Modulation of NMDARs’ function… Expand
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2015
2015
BackgroundSustained changes in network activity cause homeostatic synaptic plasticity in part by altering the postsynaptic… Expand
2015
2015
Significance In neurons, STEP61 (striatal-enriched protein tyrosine phosphatase) protein levels are tightly regulated, and the… Expand
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2014
2014
The STriatal‐Enriched protein tyrosine Phosphatase 61 (STEP61) inhibits the activity of the tyrosine kinase Fyn and… Expand
Highly Cited
2013
Highly Cited
2013
It is reported that the amyloid-β protein (Aβ)-induced impairments in synaptic plasticity coincide with memory decline and… Expand
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Highly Cited
2012
Highly Cited
2012
Glutamatergic signaling through N-methyl-D-aspartate receptors (NMDARs) is required for synaptic plasticity. Disruptions in… Expand
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2012
2012
While stressful life events confer increased risk for the development of psychopathology, most individuals experiencing adversity… Expand
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Highly Cited
2010
Highly Cited
2010
Amyloid β (Aβ) is involved in the etiology of Alzheimer's disease (AD) and may contribute to cognitive deficits by increasing… Expand
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1999
1999
Striatal enriched phosphatase (STEP) is a family of protein tyrosine phosphatases enriched within the CNS. A member of this… Expand
Highly Cited
1996
Highly Cited
1996
The STEP family of protein tyrosine phosphatases is highly enriched within the CNS. Members of this family are alternatively… Expand
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