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PTPN5 gene

Known as: PTPSTEP, STEP, striatal-enriched protein tyrosine phosphatase 
National Institutes of Health

Papers overview

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2019
2019
Dysregulated excitability within the spinal dorsal horn is a critical mediator of chronic pain. Dedek et al. report that… 
Highly Cited
2016
Highly Cited
2016
Significance NMDA receptors (NMDARs) are principal regulators of synaptic signaling in the brain. Modulation of NMDARs’ function… 
2015
2015
Brain-derived neurotrophic factor (BDNF) promotes synaptic strengthening through the regulation of kinase and phosphatase… 
2014
2014
The STriatal‐Enriched protein tyrosine Phosphatase 61 (STEP61) inhibits the activity of the tyrosine kinase Fyn and… 
Highly Cited
2012
Highly Cited
2012
Glutamatergic signaling through N-methyl-D-aspartate receptors (NMDARs) is required for synaptic plasticity. Disruptions in… 
2012
2012
While stressful life events confer increased risk for the development of psychopathology, most individuals experiencing adversity… 
Highly Cited
2010
Highly Cited
2010
Amyloid β (Aβ) is involved in the etiology of Alzheimer's disease (AD) and may contribute to cognitive deficits by increasing… 
1999
1999
Striatal enriched phosphatase (STEP) is a family of protein tyrosine phosphatases enriched within the CNS. A member of this… 
Highly Cited
1996
Highly Cited
1996
The STEP family of protein tyrosine phosphatases is highly enriched within the CNS. Members of this family are alternatively…