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PTPN21 wt Allele

Known as: DJ1175B15.2 (Protein Tyrosine Phosphatase, Non-Receptor Type 21) Gene, Protein Tyrosine Phosphatase, Non-Receptor Type 21 wt Allele, Protein-Tyrosine Phosphatase, Nonreceptor-Type, 21 Gene 
Human PTPN21 wild-type allele is located in the vicinity of 14q31.3 and is approximately 89 kb in length. This allele, which encodes tyrosine-protein… Expand
National Institutes of Health

Related topics

Related topics

8 relations
Cell Differentiation processCell ProliferationDephosphorylationHydrolysis
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Dynamic Recruitment of Protein Tyrosine Phosphatase PTPD1 to EGF Stimulation Sites Potentiates EGFR Activation
Balanced activity of protein tyrosine kinases and phosphatases (PTPs) controls tyrosine phosphorylation levels and, consequently… Expand
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Review
2013
Review
2013
The molecular and cellular characterization of a non-receptor protein tyrosine phosphatase.
Tyrosine phosphorylation of proteins is a physiologically important post-translational modification catalyzed by tyrosine kinases… Expand
2010
2010
PTPD1 Supports Receptor Stability and Mitogenic Signaling in Bladder Cancer Cells*
PTPD1, a cytosolic non-receptor protein-tyrosine phosphatase, stimulates the Src-EGF transduction pathway. Localization of PTPD1… Expand
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Highly Cited
2008
Highly Cited
2008
Protein-tyrosine Phosphatase PTPD1 Regulates Focal Adhesion Kinase Autophosphorylation and Cell Migration*
PTPD1 is a cytosolic nonreceptor tyrosine phosphatase and a positive regulator of the Src-epidermal growth factor transduction… Expand
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Highly Cited
2004
Highly Cited
2004
Mitochondrial AKAP121 Binds and Targets Protein Tyrosine Phosphatase D1, a Novel Positive Regulator of src Signaling
ABSTRACT A-kinase anchor protein 121 (AKAP121) and its spliced isoform AKAP84 anchor protein kinase A (PKA) to the outer membrane… Expand
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2000
2000
Protein-tyrosine Phosphatase D1, a Potential Regulator and Effector for Tec Family Kinases*
Etk, also named Bmx, is a member of the Tec tyrosine kinase family, which is characterized by a multimodular structure including… Expand
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Review
2000
Review
2000
Expression of protein tyrosine phosphatases and its significance in esophageal cancer.
Expression of mRNA protein tyrosine phosphatases (PTPs) was surveyed in an esophageal cancer cell line by RT-PCR using degenerate… Expand
Highly Cited
1994
Highly Cited
1994
Src kinase associates with a member of a distinct subfamily of protein-tyrosine phosphatases containing an ezrin-like domain.
A 6.2-kb full-length clone encoding a distinct protein-tyrosine phosphatase (PTP; EC 3.1.3.48), PTPD1, was isolated from a human… Expand
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