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PTPN13 wt Allele

Known as: PTP1E, Protein Tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) wt Allele, PTPLE 
Human PTPN13 wild-type allele is located in the vicinity of 4q21.3 and is approximately 221 kb in length. This allele, which encodes tyrosine-protein… 
National Institutes of Health

Related topics

Related topics

8 relations
4q21.3Cell Differentiation processCell ProliferationDephosphorylation

Papers overview

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Highly Cited
2015
Highly Cited
2015
Agent Behavior in the Sharing Economy : Evidence from Airbnb
One of the major differences between markets that follow a " sharing economy " paradigm and traditional two-sided markets is that… 
Highly Cited
2013
Highly Cited
2013
FBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascade
F-box proteins are the substrate-recognition subunits of SCF (Skp1/Cul1/F-box protein) ubiquitin ligase complexes. Purification… 
Highly Cited
2010
Highly Cited
2010
miR-200c regulates induction of apoptosis through CD95 by targeting FAP-1.
Highly Cited
2007
Highly Cited
2007
Differential redox regulation within the PTP superfamily.
Highly Cited
2006
Highly Cited
2006
Opposite Roles of FAP-1 and Dynamin in the Regulation of Fas (CD95) Translocation to the Cell Surface and Susceptibility to Fas Ligand-mediated Apoptosis*
Human melanoma is the most aggressive form of skin cancer and is extremely resistant to radiation and chemotherapy. One of the… 
Highly Cited
2006
Highly Cited
2006
Genetic characterization of fas-associated phosphatase-1 as a putative tumor suppressor gene on chromosome 4q21.3 in hepatocellular carcinoma.
PURPOSE: Allelic loss at chromosome 4q21-23 occurs frequently in human hepatocellular carcinoma, and the putative tumor… 
Highly Cited
2005
Highly Cited
2005
PTPL1 is a direct transcriptional target of EWS-FLI1 and modulates Ewing's Sarcoma tumorigenesis
Ewing's Sarcoma family tumors (ESFT) are characterized by a translocation t(11:22) forming an aberrant transcription factor EWS… 
Highly Cited
2003
Highly Cited
2003
Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.
It has been postulated that PtdIns(3,4) P (2), one of the immediate breakdown products of PtdIns(3,4,5) P (3), functions as a… 
Highly Cited
2001
Highly Cited
2001
FAP-1 in pancreatic cancer cells: functional and mechanistic studies on its inhibitory role in CD95-mediated apoptosis.
In this study we investigated the functional role of FAP-1 as a potential inhibitor of CD95 (Fas, APO-1)-mediated apoptosis in… 
Highly Cited
2001
Highly Cited
2001
Expression and potential role of Fas-associated phosphatase-1 in ovarian cancer.
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