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PSI-421
Known as:
PSI 421
, PSI421
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Hydroxyquinolines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Discovery of 2-[1-(4-chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic acid (PSI-421), a P-selectin inhibitor with improved pharmacokinetic properties and oral efficacy in…
A. Huang
,
A. Moretto
,
+13 authors
N. Kaila
Journal of medicinal chemistry
2010
Corpus ID: 207238892
Previously, we reported the discovery of PSI-697 (1a), a C-2 benzyl substituted quinoline salicylic acid-based P-selectin…
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Highly Cited
2008
Highly Cited
2008
Prophylactic P-selectin inhibition with PSI-421 promotes resolution of venous thrombosis without anticoagulation.
Thomas R Meier
,
D. Myers
,
+9 authors
T. Wakefield
Thrombosis and haemostasis
2008
Corpus ID: 30013273
P-selectin inhibition has been evaluated as a therapeutic for prevention and treatment of venous thrombosis. In this study, a…
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