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PSAP wt Allele

Known as: Prosaposin wt Allele, GLBA, SAP1 
Human PSAP wild-type allele is located within 10q21-q22 and is approximately 35 kb in length. This allele, which encodes proactivator polypeptide… 
National Institutes of Health

Related topics

Related topics

4 relations
10q21-q22Lipid MetabolismLipid TransportPlatelet Activation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Role of Candida albicans-Secreted Aspartyl Proteinases (Saps) in Severe Early Childhood Caries
Candida albicans is strongly associated with severe early childhood caries (S-ECC). However, the roles of secreted aspartyl… 
Highly Cited
2010
Highly Cited
2010
Limited Role of Secreted Aspartyl Proteinases Sap1 to Sap6 in Candida albicans Virulence and Host Immune Response in Murine Hematogenously Disseminated Candidiasis
ABSTRACT Candida albicans secreted aspartyl proteinases (Saps) are considered virulence-associated factors. Several members of… 
Highly Cited
2008
Highly Cited
2008
X‐ray structures of Sap1 and Sap5: Structural comparison of the secreted aspartic proteinases from Candida albicans
Proteolytic activity is an important virulence factor for Candida albicans (C. albicans). It is attributed to the family of the… 
2007
2007
Sap1 Promotes the Association of the Replication Fork Protection Complex With Chromatin and Is Involved in the Replication Checkpoint in Schizosaccharomyces pombe
Sap1 is involved in replication fork pausing at rDNA repeats and functions during mating-type switching in Schizosaccharomyces… 
2007
2007
The crystal structure of the secreted aspartic proteinase 3 from Candida albicans and its complex with pepstatin A
The family of secreted aspartic proteinases (Sap) encoded by 10 SAP genes is an important virulence factor during Candida… 
Highly Cited
2005
Highly Cited
2005
Candida albicans-Secreted Aspartic Proteinases Modify the Epithelial Cytokine Response in an In Vitro Model of Vaginal Candidiasis
ABSTRACT Secreted aspartyl proteinases (Saps) are important virulence factors of Candida albicans during mucosal and disseminated… 
Highly Cited
2001
Highly Cited
2001
Capital Market Reactions to the Passage of the Financial Services Modernization Act of 1999
The Financial Services Modernization Act of 1999, also known as the Gramm-Leach-Bliley Act (GLBA), removed most of the remaining… 
2000
2000
Solution structural studies and low-resolution model of the Schizosaccharomyces pombe sap1 protein.
Sap1 is a DNA-binding protein involved in controlling the mating type switch in fission yeast Schizosaccharomyces pombe. In the… 
Highly Cited
1999
Highly Cited
1999
Secreted aspartic proteinase (Sap) activity contributes to tissue damage in a model of human oral candidosis
Secreted aspartic proteinases (Saps) are important virulence factors during Candida albicans mucosal or disseminated infections… 
Highly Cited
1994
Highly Cited
1994
A fourth secreted aspartyl proteinase gene (SAP4) and a CARE2 repetitive element are located upstream of the SAP1 gene in Candida albicans
Candida albicans secreted aspartyl proteinases (Sap), products of the SAP genes, which are presumed to act as virulence factors… 
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