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PRKX gene

Known as: PRKX, PKX1, PROTEIN KINASE PKX1 
National Institutes of Health

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PRKXP1 gene

Papers overview

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2018
2018
Abstract 4456: Increased NTF2 levels in melanoma cell lines affect nuclear size and cancer cell characteristics
Xenopus studies have implicated two nuclear transport factors in the regulation of nuclear size: NTF2 and importin α. Importin… 
2016
2016
Altered Expression of PRKX, WNT3 and WNT16 in Human Nodular Basal Cell Carcinoma.
BACKGROUND/AIM Nodular and superficial are the most common subtypes of basal cell carcinoma (BCC). Signaling pathways such as… 
2016
2016
Abstract P6-03-20: Gene expression profile of triple negative breast cancer in patients highlight biomarkers involved in cell metabolism
Introduction: Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype, lacking expression of estrogen… 
2014
2014
Transforming Growth Factor (TGF)-β-activated Kinase 1 (TAK1) Activation Requires Phosphorylation of Serine 412 by Protein Kinase A Catalytic Subunit α (PKACα) and X-linked Protein Kinase (PRKX)*
Background: Understanding of molecular mechanism of TAK1 activation is incomplete. Results: PKACα and PRKX phosphorylate TAK1 at… 
2012
2012
PRKX, TTBK2 and RSK4 expression causes sunitinib resistance in kidney carcinoma‐ and melanoma‐cell lines
Resistance to chemotherapeutic agents constitutes a major problem in the treatment of cancer. Over the past years, multi‐targeted… 
2011
2011
PRKX critically regulates endothelial cell proliferation, migration, and vascular-like structure formation.
2002
2002
Adeno-Associated Virus Type 2 Rep78 Inhibition of PKA and PRKX: Fine Mapping and Analysis of Mechanism
ABSTRACT Hormones and neurotransmitters utilize cyclic AMP (cAMP) as a second messenger in signal transduction pathways to… 
Highly Cited
1998
Highly Cited
1998
Inhibition of PrKX, a Novel Protein Kinase, and the Cyclic AMP-Dependent Protein Kinase PKA by the Regulatory Proteins of Adeno-Associated Virus Type 2
ABSTRACT Adeno-associated virus encodes four nonstructural proteins, which are known as Rep78, Rep68, Rep52, and Rep40… 
Highly Cited
1997
Highly Cited
1997
Abnormal XY interchange between a novel isolated protein kinase gene, PRKY, and its homologue, PRKX, accounts for one third of all (Y+)XX males and (Y-)XY females.
XX males and XY females have a sex reversal disorder which can be caused by an abnormal interchange between the X and the Y… 
Highly Cited
1995
Highly Cited
1995
The human protein kinase gene PKX1 on Xp22.3 displays Xp/Yp homology and is a site of chromosomal instability.
We have isolated a gene, PKX1, by virtue of its position within the candidate region for chondrodysplasia punctata in Xp22.3… 
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