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PRKX gene

Known as: PRKX, PKX1, PROTEIN KINASE PKX1 
 
National Institutes of Health

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PRKXP1 gene

Papers overview

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2016
2016
Altered Expression of PRKX, WNT3 and WNT16 in Human Nodular Basal Cell Carcinoma.
BACKGROUND/AIM Nodular and superficial are the most common subtypes of basal cell carcinoma (BCC). Signaling pathways such as… Expand
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2016
2016
Abstract P6-03-20: Gene expression profile of triple negative breast cancer in patients highlight biomarkers involved in cell metabolism
Introduction: Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype, lacking expression of estrogen… Expand
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2014
2014
Transforming Growth Factor (TGF)-β-activated Kinase 1 (TAK1) Activation Requires Phosphorylation of Serine 412 by Protein Kinase A Catalytic Subunit α (PKACα) and X-linked Protein Kinase (PRKX)*
Background: Understanding of molecular mechanism of TAK1 activation is incomplete. Results: PKACα and PRKX phosphorylate TAK1 at… Expand
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2012
2012
PRKX, TTBK2 and RSK4 expression causes Sunitinib resistance in kidney carcinoma- and melanoma-cell lines.
Resistance to chemotherapeutic agents constitutes a major problem in the treatment of cancer. Over the past years, multi-targeted… Expand
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2011
2011
PRKX critically regulates endothelial cell proliferation, migration, and vascular-like structure formation.
Angiogenesis is a fundamental step in several important physiological events and pathological conditions including embryonic… Expand
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2002
2002
Adeno-associated virus type 2 Rep78 inhibition of PKA and PRKX: fine mapping and analysis of mechanism.
Hormones and neurotransmitters utilize cyclic AMP (cAMP) as a second messenger in signal transduction pathways to regulate cell… Expand
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1998
1998
Inhibition of PrKX, a novel protein kinase, and the cyclic AMP-dependent protein kinase PKA by the regulatory proteins of adeno-associated virus type 2.
Adeno-associated virus encodes four nonstructural proteins, which are known as Rep78, Rep68, Rep52, and Rep40. Expression of… Expand
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1998
1998
Adeno-associated virus Rep78 protein interacts with protein kinase A and its homolog PRKX and inhibits CREB-dependent transcriptional activation.
Adeno-associated virus (AAV) is a human parvovirus of the genus Dependovirus. AAV replication is largely restricted to cells… Expand
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Highly Cited
1997
Highly Cited
1997
Abnormal XY interchange between a novel isolated protein kinase gene, PRKY, and its homologue, PRKX, accounts for one third of all (Y+)XX males and (Y-)XY females.
XX males and XY females have a sex reversal disorder which can be caused by an abnormal interchange between the X and the Y… Expand
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1995
1995
The human protein kinase gene PKX1 on Xp22.3 displays Xp/Yp homology and is a site of chromosomal instability.
We have isolated a gene, PKX1, by virtue of its position within the candidate region for chondrodysplasia punctata in Xp22.3… Expand
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