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PRIMPOL gene

Known as: primase and DNA directed polymerase, CCDC111, COILED-COIL DOMAIN CONTAINING 111 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
PRIMPOL variants cause multi-system mitochondrial disorder
2020
2020
Identifying the role of PrimPol in TDF-induced toxicity and implications of its loss of function mutation in an HIV+ patient
A key component of antiretroviral therapy (ART) for HIV patients is the nucleoside reverse transcriptase inhibitor (NRTI) is… 
2017
2017
Current and Emerging Assays for Studying the Primer Synthesis Activities of DNA Primases.
Review
2017
Review
2017
An investigation into the role, recruitment, and regulation of PrimPol in DNA replication restart
DNA replication is one of life's fundamental processes. This delicate task is performed by a complex of molecular machines, known… 
2015
2015
Author response: PRIMPOL mutation: functional study does not always reveal the truth.
Although the findings reported in this letter by Li and Zhang may challenge the conclusions of Zhao et al., who originally… 
2015
2015
Molecular dissection of PrimPol, a novel primase-polymerase involved in damage tolerance during DNA replication in eukaryotic cells
PrimPol is a recently identified member of the archaeo-eukaryotic primase (AEP) family of proteins. It possesses both primase… 
2013
2013
PrimPol breaks replication barriers
  • T. Helleday
  • Nature Structural &Molecular Biology
  • 2013
  • Corpus ID: 11756625
Faithful bypass of replication forks encountering obstructive DNA lesions is essential to prevent fork collapse and cell death… 
2013
2013
Human Primpol1: a novel guardian of stalled replication forks
The successful duplication of genomic DNA during S phase is essential for the proper transmission of genetic information to the… 
2013
2013
Investigating the role of a novel primase-polymerase, PrimPol, in DNA damage tolerance in vertebrate cells
Genome duplication is an essential task our cells have to achieve prior to cell division, and requires a highly specialized… 
2013
2013
PrimPol bypasses UV photoproducts during chromosomal DNA replication
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