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PRICKLE1 wt Allele
Known as:
RILP
, Prickle Planar Cell Polarity Protein 1 wt Allele
, Prickle Homolog 1 (Drosophila) Gene
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Human PRICKLE1 wild-type allele is located in the vicinity of 12q12 and is approximately 134 kb in length. This allele, which encodes prickle-like…
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National Institutes of Health
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Related topics
Related topics
5 relations
12q12
Morphogenesis
PRICKLE1 gene
Signal Transduction
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
A RILP-regulated pathway coordinating autophagosome biogenesis with transport.
Noopur V Khobrekar
,
R. Vallee
Autophagy
2020
Corpus ID: 220253893
Mammalian cells, including neurons, use macroautophagy (here 'autophagy') to degrade damaged proteins and organelles, and recycle…
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2019
2019
RILP Restricts Insulin Secretion Through Mediating Lysosomal Degradation of Proinsulin
Yuxia Zhou
,
Zhiyu Liu
,
+9 authors
Tuanlao Wang
Diabetes
2019
Corpus ID: 204773384
Insulin secretion is tightly regulated by membrane trafficking. RILP (Rab7 interacting lysosomal protein) regulates the endocytic…
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2016
2016
Hepatitis C virus promotes virion secretion through cleavage of the Rab7 adaptor protein RILP
A. Wozniak
,
A. Long
,
Kellyann N Jones-Jamtgaard
,
S. Weinman
Proceedings of the National Academy of Sciences
2016
Corpus ID: 19603626
Significance Viruses frequently alter cellular processes to promote their own lifecycle, whereas cells adapt by initiating…
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2015
2015
RILP suppresses invasion of breast cancer cells by modulating the activity of RalA through interaction with RalGDS
Z. Wang
,
Y. Zhou
,
+6 authors
T. Wang
Cell Death and Disease
2015
Corpus ID: 38047617
RILP (Rab7-interacting lysosomal protein) is a key regulator for late endosomal/lysosomal trafficking, and probably a tumor…
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2010
2010
Rab36 regulates the spatial distribution of late endosomes and lysosomes through a similar mechanism to Rab34
Li Chen
,
Jingjie Hu
,
Ye Yun
,
Tuanlao Wang
Molecular membrane biology
2010
Corpus ID: 23760748
Abstract Small GTPase Rab36 is homologous to Rab34 with 56% amino acid sequence identity. Rab34 was characterized as a Golgi…
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2010
2010
Relationship between Comfort Meter values and the prickle rating of garments in wearer trials
D. Tester
2010
Corpus ID: 55595625
The latest prototype version of the CSIRO-developed Comfort Meter was used to measure representative samples of all the garments…
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Highly Cited
2007
Highly Cited
2007
RILP is required for the proper morphology and function of late endosomes
C. Progida
,
L. Malerød
,
Susanne Stuffers
,
A. Brech
,
C. Bucci
,
H. Stenmark
Journal of Cell Science
2007
Corpus ID: 22594121
Lysosomal degradation of signalling receptors such as the epidermal growth factor (EGF) receptor (EGFR) is an important mechanism…
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2006
2006
Splice variant of the Rab 7 effector RILP induces lysosomal clustering without dynein motor recruitment
M. Marsman
,
I. Jordens
,
Nuno Rocha
,
C. Kuijl
,
L. Janssen
,
J. Neefjes
2006
Corpus ID: 30675242
The small GTPase Rab7 controls fusion and transport of late endocytic compartments. A critical mediator is the Rab7 effector RILP…
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Highly Cited
2004
Highly Cited
2004
Microtubule motors control membrane dynamics of Salmonella-containing vacuoles
J. Guignot
,
E. Caron
,
+4 authors
D. Holden
Journal of Cell Science
2004
Corpus ID: 7527839
Infection of host cells by Salmonella enterica serovar Typhimurium (S. typhimurium) leads to the formation of specialised…
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Highly Cited
2003
Highly Cited
2003
A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34.
Tuanlao Wang
,
Katy K. Wong
,
W. Hong
Molecular Biology of the Cell
2003
Corpus ID: 9657653
Rab7 and Rab34 are implicated in regulation of lysosomal morphology and they share a common effector referred to as the RILP (Rab…
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