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PRICKLE1 wt Allele

Known as: RILP, Prickle Planar Cell Polarity Protein 1 wt Allele, Prickle Homolog 1 (Drosophila) Gene 
Human PRICKLE1 wild-type allele is located in the vicinity of 12q12 and is approximately 134 kb in length. This allele, which encodes prickle-like… 
National Institutes of Health

Related topics

Related topics

5 relations
12q12MorphogenesisPRICKLE1 geneSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
A RILP-regulated pathway coordinating autophagosome biogenesis with transport.
Mammalian cells, including neurons, use macroautophagy (here 'autophagy') to degrade damaged proteins and organelles, and recycle… 
2019
2019
RILP Restricts Insulin Secretion Through Mediating Lysosomal Degradation of Proinsulin
Insulin secretion is tightly regulated by membrane trafficking. RILP (Rab7 interacting lysosomal protein) regulates the endocytic… 
2016
2016
Hepatitis C virus promotes virion secretion through cleavage of the Rab7 adaptor protein RILP
Significance Viruses frequently alter cellular processes to promote their own lifecycle, whereas cells adapt by initiating… 
2015
2015
RILP suppresses invasion of breast cancer cells by modulating the activity of RalA through interaction with RalGDS
RILP (Rab7-interacting lysosomal protein) is a key regulator for late endosomal/lysosomal trafficking, and probably a tumor… 
2010
2010
Rab36 regulates the spatial distribution of late endosomes and lysosomes through a similar mechanism to Rab34
Abstract Small GTPase Rab36 is homologous to Rab34 with 56% amino acid sequence identity. Rab34 was characterized as a Golgi… 
2010
2010
Relationship between Comfort Meter values and the prickle rating of garments in wearer trials
The latest prototype version of the CSIRO-developed Comfort Meter was used to measure representative samples of all the garments… 
Highly Cited
2007
Highly Cited
2007
RILP is required for the proper morphology and function of late endosomes
Lysosomal degradation of signalling receptors such as the epidermal growth factor (EGF) receptor (EGFR) is an important mechanism… 
2006
2006
Splice variant of the Rab 7 effector RILP induces lysosomal clustering without dynein motor recruitment
The small GTPase Rab7 controls fusion and transport of late endocytic compartments. A critical mediator is the Rab7 effector RILP… 
Highly Cited
2004
Highly Cited
2004
Microtubule motors control membrane dynamics of Salmonella-containing vacuoles
Infection of host cells by Salmonella enterica serovar Typhimurium (S. typhimurium) leads to the formation of specialised… 
Highly Cited
2003
Highly Cited
2003
A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34.
Rab7 and Rab34 are implicated in regulation of lysosomal morphology and they share a common effector referred to as the RILP (Rab… 
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